Sign in or Register

IZUMO1R

IZUMO1R (IZUMO1 Receptor, JUNO) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Antifolate resistance. Gene Ontology (GO) annotations related to this gene include receptor activity and folic acid binding. An important paralog of this gene is FOLR1.
Full Name
IZUMO1 Receptor, JUNO
Function
Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.
Biological Process
Cell adhesionISS:UniProtKB
Fusion of sperm to egg plasma membrane involved in single fertilizationISS:UniProtKB
Single fertilizationISS:UniProtKB
Sperm-egg recognitionISS:UniProtKB
Cellular Location
Cell membrane. GPI-anchored at the oolemma.
PTM
The protein is rapidly cleaved following fertilization, being only weakly detectable in zona-intact fertilized eggs at telophase II and undetectable at the pronuclear stage. Sheding is probably required to block to polyspermy and ensuring egg fusion with a single sperm.
View more

Anti-IZUMO1R antibodies

+ Filters
Loading...

Rat Anti-IZUMO1R Recombinant Antibody (CBXF-2698) (CBMAB-F3100-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXF-2698
Application*: WB
Datasheet SDS

Rat Anti-IZUMO1R (AA 134-210) Recombinant Antibody (CBXF-2697) (CBMAB-F3099-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-2697
Application*: IH
Datasheet SDS

Rat Anti-IZUMO1R Recombinant Antibody (CBXF-2269) (CBMAB-F2599-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: CBXF-2269
Application*: F, FN, IP
Datasheet SDS

Rat Anti-IZUMO1R Recombinant Antibody (CBXF-1525) (CBMAB-F0502-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: CBXF-1525
Application*: F
Datasheet SDS

Rat Anti-IZUMO1R Recombinant Antibody (TH6) (CBMAB-F0090-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: TH6
Application*: F, MC
Datasheet SDS

Rat Anti-IZUMO1R Recombinant Antibody (12A5) (CBMAB-F0089-CQ)

Go to compareCompare
Target: IZUMO1R
Host: Rat
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: 12A5
Application*: IS
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry