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LMO2

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur.
Full Name
LIM domain only 2
Function
Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
Biological Process
Cellular response to thyroid hormone stimulusManual Assertion Based On ExperimentIDA:UniProtKB
Multicellular organism developmentManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.

Anti-LMO2 antibodies

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Mouse Anti-LMO2 Recombinant Antibody (CBYCL-397) (CBMAB-L0298-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYCL-397
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYCL-396) (CBMAB-L0297-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-396
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYCL-395) (CBMAB-L0296-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-395
Application*: E, WB, F

Mouse Anti-LMO2 Recombinant Antibody (CBYCL-394) (CBMAB-L0295-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-394
Application*: IH, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYCL-393) (CBMAB-L0294-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYCL-393
Application*: IF, P, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYCL-392) (CBMAB-L0293-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYCL-392
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (1A9-3D11) (CBMAB-R0573-CN)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A9-3D11
Application*: P

Rabbit Anti-LMO2 Recombinant Antibody (SP51) (CBMAB-L1874-YJ)

Datasheet SDS
Target: LMO2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP51
Application*: P, WB, F

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1877) (CBMAB-L1873-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1877
Application*: WB, IP, IF, E

Rabbit Anti-LMO2 Recombinant Antibody (EP3257) (CBMAB-L1872-YJ)

Datasheet SDS
Target: LMO2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EP3257
Application*: F, IP, WB

Mouse Anti-LMO2 Recombinant Antibody (6B8) (CBMAB-L1871-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6B8
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1876) (CBMAB-L1870-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYJL-1876
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (4D8) (CBMAB-L1869-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4D8
Application*: WB, F

Mouse Anti-LMO2 Recombinant Antibody (4D3) (CBMAB-L1868-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4D3
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1875) (CBMAB-L1866-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1875
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1873) (CBMAB-L1864-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-1873
Application*: WB

Mouse Anti-LMO2 Recombinant Antibody (2D7) (CBMAB-L1863-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D7
Application*: WB

Mouse Anti-LMO2 Recombinant Antibody (2B3) (CBMAB-L1862-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2B3
Application*: E, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1872) (CBMAB-L1861-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1872
Application*: WB, IH

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1870) (CBMAB-L1859-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1870
Application*: P, WB

Mouse Anti-LMO2 Recombinant Antibody (CBYJL-1869) (CBMAB-L1858-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1869
Application*: P

Mouse Anti-LMO2 Recombinant Antibody (1A9-3B11) (CBMAB-L1857-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A9-3B11
Application*: WB, IH, IC, IF, P

Mouse Anti-LMO2 Recombinant Antibody (1A9-1) (CBMAB-L1856-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1A9-1
Application*: WB, P, IC, IF

Rabbit Anti-LMO2 Recombinant Antibody (CBYJL-1868) (CBMAB-L1855-YJ)

Datasheet SDS
Target: LMO2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1868
Application*: F, WB

Mouse Anti-LMO2 Recombinant Antibody (13B477) (CBMAB-L1854-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B477
Application*: E, F, WB

Mouse Anti-LMO2 Recombinant Antibody (10D368) (CBMAB-L1853-YJ)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10D368
Application*: IF, IH, WB

Mouse Anti-LMO2 Recombinant Antibody (IHC615) (CBMAB-MA151-YC)

Datasheet SDS
Target: LMO2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: IHC615
Application*: P, E, IH
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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