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MMP11

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
Full Name
Matrix Metallopeptidase 11
Function
May play an important role in the progression of epithelial malignancies.
Biological Process
Basement membrane organization Source: Ensembl
Collagen catabolic process Source: GO_Central
Collagen fibril organization Source: Ensembl
Extracellular matrix disassembly Source: Reactome
Extracellular matrix organization Source: GO_Central
Multicellular organism development Source: ProtInc
Negative regulation of fat cell differentiation Source: Ensembl
Proteolysis Source: ProtInc
Cellular Location
Extracellular matrix
PTM
The precursor is cleaved by a furin endopeptidase.
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Anti-MMP11 antibodies

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Mouse Anti-MMP11 Recombinant Antibody (CBFYM-0416) (CBMAB-M0529-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0416
Application*: P, IP, WB
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (A1137) (CBMAB-AP4386LY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: A1137
Application*: ICC, IHC, IP, WB
Datasheet SDS

Recombinant Mouse Anti-MMP11 Recombinant Antibody (4A9) (CBMAB-XB0820-YC)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4A9
Application*: E, IH, IF, WB
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBXS-5126) (CBMAB-S2344-CQ)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-5126
Application*: WB, IC, P, C, E, IP, IF, F
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBFYM-2352) (CBMAB-M2538-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBFYM-2352
Application*: C, P
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBFYM-2351) (CBMAB-M2537-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-2351
Application*: IP, WB
Datasheet SDS

Mouse Anti-MMP11 (AA 277-488) Recombinant Antibody (CBFYM-2350) (CBMAB-M2536-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2350
Application*: E, WB
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBFYM-2349) (CBMAB-M2535-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2349
Application*: WB, IC, C, P, E
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBFYM-0665) (CBMAB-M0801-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0665
Application*: IH, IP, WB
Datasheet SDS

Mouse Anti-MMP11 (AA 277-488) Recombinant Antibody (CBFYM-0519) (CBMAB-M0647-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0519
Application*: E, IC, WB
Datasheet SDS

Mouse Anti-MMP11 Recombinant Antibody (CBFYM-0049) (CBMAB-M0055-FY)

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Target: MMP11
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYM-0049
Application*: F
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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