NRV1

NRV1 (nervana protein) is β subunit of the Na+/K+ ATPase that differ in their cytoplasmic tails. It has shown that NRV1 is nervous system specific.

Full Name

nrv1

Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

Biological Process

Cation transportManual Assertion Based On ExperimentIDA:FlyBase
Cellular potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Cellular sodium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of P-type sodium:potassium-exchanging transporter activityManual Assertion Based On ExperimentIDA:FlyBase
Potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Sodium ion export across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-45
Helical: 46-66
Extracellular: 67-309