Mouse Anti-NRV1 Antibody (Nrv 5F7) (CBMAB-0892-YC)

Name: Mouse Anti-NRV1 Antibody (Nrv 5F7)
SKU: CBMAB-0892-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

Nrv 5F7

Application

Specificity

Common fruit fly

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

nrv1

Introduction

NRV1 (nervana protein) is β subunit of the Na+/K+ ATPase that differ in their cytoplasmic tails. It has shown that NRV1 is nervous system specific.

Entrez Gene ID

33952

UniProt ID

B5RIR1

Alternative Names

42kDa; CG9258; Dmel\CG9258; K-ATPase; Na; NaK ATPase; Na[+]/K[+] ATPase; Na[+]/K[+]-ATPase; Na[+]/K[+]ATPase; nervana; NKA-alpha; Nrv; Nrv1

Function

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

Biological Process

Cation transportManual Assertion Based On ExperimentIDA:FlyBase
Cellular potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Cellular sodium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of P-type sodium:potassium-exchanging transporter activityManual Assertion Based On ExperimentIDA:FlyBase
Potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Sodium ion export across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Topology

Cytoplasmic: 1-45
Helical: 46-66
Extracellular: 67-309

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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