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Mouse Anti-NRV1 Antibody (Nrv 5F7) (CBMAB-0892-YC)

Provided herein are mouse monoclonal antibodies against Drosophila NRV1. The antibody clone Nrv5F7 can be used for immunoassay techniques, such as WB.
See all NRV1 antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
Nrv 5F7
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Common fruit fly
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
nrv1
Introduction
NRV1 (nervana protein) is β subunit of the Na+/K+ ATPase that differ in their cytoplasmic tails. It has shown that NRV1 is nervous system specific.
Entrez Gene ID
33952
UniProt ID
B5RIR1
Alternative Names
42kDa; CG9258; Dmel\CG9258; K-ATPase; Na; NaK ATPase; Na[+]/K[+] ATPase; Na[+]/K[+]-ATPase; Na[+]/K[+]ATPase; nervana; NKA-alpha; Nrv; Nrv1
Function
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Biological Process
Cation transportManual Assertion Based On ExperimentIDA:FlyBase
Cellular potassium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Cellular sodium ion homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of P-type sodium:potassium-exchanging transporter activityManual Assertion Based On ExperimentIDA:FlyBase
Potassium ion import across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Sodium ion export across plasma membraneManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-45
Helical: 46-66
Extracellular: 67-309
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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