PDLIM5

The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized. [provided by RefSeq]
Full Name
PDZ and LIM domain 5
Function
May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity).
Biological Process
Actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Cell growth involved in cardiac muscle cell developmentISS:BHF-UCL
Heart developmentManual Assertion Based On ExperimentIBA:GO_Central
Muscle structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Regulation of dendritic spine morphogenesisISS:UniProtKB
Regulation of synapse assemblyISS:UniProtKB
Cellular Location
Cell junction, synapse, postsynaptic density
Cell junction, synapse, presynapse
Cell junction, synapse, postsynapse
Cytoplasm, cytosol
Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons.
View more

Anti-PDLIM5 antibodies

+ Filters
Loading...

Mouse Anti-PDLIM5 Recombinant Antibody (CBYC-P274) (CBMAB-P1338-YC)

Go to compareCompare
Target: PDLIM5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYC-P274
Application*: E, IC, WB
Datasheet SDS

Mouse Anti-PDLIM5 Recombinant Antibody (3E11-F6) (CBMAB-P1337-YC)

Go to compareCompare
Target: PDLIM5
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3E11-F6
Application*: IF, WB
Datasheet SDS

Mouse Anti-PDLIM5 Recombinant Antibody (1H10) (CBMAB-P1336-YC)

Go to compareCompare
Target: PDLIM5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1H10
Application*: WB, F
Datasheet SDS

Mouse Anti-PDLIM5 Recombinant Antibody (1B5) (CBMAB-P1335-YC)

Go to compareCompare
Target: PDLIM5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B5
Application*: WB
Datasheet SDS

Mouse Anti-PDLIM5 Recombinant Antibody (1A11) (CBMAB-P1334-YC)

Go to compareCompare
Target: PDLIM5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1A11
Application*: F, WB
Datasheet SDS

Human PDLIM5 ELISA Kit (V2LY-0626-LY5000)

Go to compareCompare
Target: PDLIM5
Sensitivity: 0.005 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.