PFKFB2

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 2
Function
Synthesis and degradation of fructose 2,6-bisphosphate.
Biological Process
Fructose 2,6-bisphosphate metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Fructose metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Glucose catabolic processIEA:Ensembl
Glycolytic processManual Assertion Based On ExperimentIDA:UniProtKB
Lactate metabolic processIEA:Ensembl
Positive regulation of glucokinase activityIEA:Ensembl
Positive regulation of insulin secretionIEA:Ensembl
Response to glucoseIEA:Ensembl
Cellular Location
cytosol
nucleoplasm
PTM
Phosphorylation by AMPK stimulates activity.
View more

Anti-PFKFB2 antibodies

+ Filters
Loading...

Rabbit Anti-PFKFB2 Recombinant Antibody (D7G5R) (CBMAB-CP1938-LY)

Go to compareCompare
Target: PFKFB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D7G5R
Application*: WB, IP, IF (IC)
Datasheet SDS

Rabbit Anti-PFKFB2 Recombinant Antibody (D5I5F) (CBMAB-CP1937-LY)

Go to compareCompare
Target: PFKFB2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D5I5F
Application*: WB, IP, IF (IC)
Datasheet SDS

Human PFKFB2 ELISA Kit (V2LY-0626-LY3680)

Go to compareCompare
Target: PFKFB2
Sensitivity: 0.017 ng/mL
Detection Range: 0.05-15 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Human Recombinant PFKFB2/PFK2 protein, GST Tag (V2LY-0526-LY6123)

Go to compareCompare
Target: PFKFB2
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: Full Length
Tag: GST Tag
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.