RXRG

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Full Name
Retinoid X Receptor Gamma
Function
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity).
Biological Process
Biological Process anatomical structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process heart developmentIEA:Ensembl
Biological Process neuron differentiationIEA:Ensembl
Biological Process peripheral nervous system developmentIEA:Ensembl
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of myelinationIEA:Ensembl
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to retinoic acidManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinoic acid receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal muscle tissue developmentIEA:Ensembl
Cellular Location
Nucleus
Cytoplasm
PTM
Acetylated by EP300.
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Anti-RXRG antibodies

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Recombinant Mouse Anti-RXRg Recombinant Antibody (12RX-2D3) (CBMAB-XB1013-YC)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Human
Clone: 12RX-2D3
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (CBWJN-1669) (CBMAB-N4241-WJ)

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Target: RXRG
Host: Mouse
Specificity: Human
Clone: CBWJN-1669
Application*: WB, IC, P, IH-F, E
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (H3210) (CBMAB-R3977-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: H3210
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (G-6) (CBMAB-R3976-CN)

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Target: RXRG
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: G-6
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (CBCNR-906) (CBMAB-R3975-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNR-906
Application*: WB
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (A-2) (CBMAB-R3974-CN)

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Target: RXRG
Host: Mouse
Specificity: Human
Clone: A-2
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (9i204) (CBMAB-R3973-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 9i204
Application*: WB
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (6H1) (CBMAB-R3972-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6H1
Application*: E, WB
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (2D3) (CBMAB-R3971-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2D3
Application*: E, WB, ICC
Datasheet SDS

Mouse Anti-RXRG Recombinant Antibody (1373) (CBMAB-R3968-CN)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: 1373
Application*: WB
Datasheet SDS

Mouse Anti-RXRG Monoclonal Antibody (5H4) (CBMAB-0069-LY)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5H4
Application*: IP, M
Datasheet SDS

Mouse Anti-RXRG Monoclonal Antibody (5G6) (CBMAB-0068-LY)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5G6
Application*: IP, M
Datasheet SDS

Mouse Anti-RXRG Monoclonal Antibody (5C9) (CBMAB-0067-LY)

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Target: RXRG
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 5C9
Application*: IP, M
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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