SLC28A2

Full Name

solute carrier family 28 (sodium-coupled nucleoside transporter), member 2

Function

Sodium-dependent and purine-selective transporter (PubMed:9435697, PubMed:10087507).
Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine) (PubMed:9435697, PubMed:10087507).
Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues (PubMed:9435697).

Biological Process

Biological Process adenosine transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process azole transmembrane transportISS:ARUK-UCL
Biological Process inosine transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process neurotransmitter transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process nucleobase-containing compound metabolic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process nucleoside transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process purine nucleobase transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process purine nucleoside transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process pyrimidine-containing compound transmembrane transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process retina homeostasisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transport across blood-brain barrier2 PublicationsNAS:ARUK-UCL
Biological Process uridine transportManual Assertion Based On ExperimentIDA:ARUK-UCL
Biological Process xenobiotic transmembrane transportTAS:Reactome

Cellular Location

Membrane