YY1AP1

The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Full Name

YY1 associated protein 1

Function

Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641).
Enhances transcription activation by YY1 (PubMed:14744866).
Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641).

Biological Process

Biological Process cell differentiation Source:UniProtKB1 Publication
Biological Process cell population proliferation Source:UniProtKB1 Publication
Biological Process regulation of cell cycle Source:UniProtKB1 Publication
Biological Process regulation of DNA-templated transcription Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Nucleus
Nucleus, nucleoplasm
Nucleus, nucleolus

Involvement in disease

Grange syndrome (GRNG):
An autosomal recessive syndrome of stenosis or occlusion of multiple arteries, including renal, abdominal, cerebral and probably coronary arteries, congenital heart defects, brachydactyly, syndactyly, bone fragility, and learning disabilities.