YY1AP1

The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Full Name

YY1 associated protein 1

Function

Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication (PubMed:27939641).
Enhances transcription activation by YY1 (PubMed:14744866).
Plays a role in cell cycle regulation (PubMed:17541814, PubMed:27939641).

Biological Process

Biological Process cell differentiation Source:UniProtKB1 Publication
Biological Process cell population proliferation Source:UniProtKB1 Publication
Biological Process regulation of cell cycle Source:UniProtKB1 Publication
Biological Process regulation of DNA-templated transcription Source:GO_Central1 Publication

Cellular Location

Cytoplasm
Nucleus
Nucleus, nucleoplasm
Nucleus, nucleolus

Involvement in disease

Grange syndrome (GRNG):
An autosomal recessive syndrome of stenosis or occlusion of multiple arteries, including renal, abdominal, cerebral and probably coronary arteries, congenital heart defects, brachydactyly, syndactyly, bone fragility, and learning disabilities.

Anti-YY1AP1 antibodies

Mouse Anti-YY1AP1 Recombinant Antibody (2G7) (CBMAB-Y0081-LY)

Datasheet

SDS

Target: YY1AP1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2G7

Application*: E, WB, IF

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)