ZMAT3
ZMAT3 is a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway.
Full Name
Zinc Finger Matrin-Type 3
Function
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process cellular response to DNA damage stimulus Source:UniProtKB-KW
Biological Process protein transport Source:UniProtKB-KW
Biological Process cellular response to DNA damage stimulus Source:UniProtKB-KW
Biological Process protein transport Source:UniProtKB-KW
Cellular Location
Nucleus
Nucleus, nucleolus
Nucleus, nucleolus
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Anti-ZMAT3 antibodies
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Target: ZMAT3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 608-45
Application*: E, IC, IF, WB
Target: ZMAT3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: 3E4
Application*: WB, P, IF
Target: ZMAT3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBWJZ-155
Application*: E, IC, IF, WB
Target: ZMAT3
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBWJW-135
Application*: WB, IP, IF, E
Target: ZMAT3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Guinea Pig
Clone: CBWJW-040
Application*: WB, P, PE
Target: ZMAT3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBWJW-039
Application*: IF
Target: ZMAT3
Sensitivity: 0.0051 ng/mL
Detection Range: 0.01-2 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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