ALDH3A1 Matched Antibody Pair (064) (APMAB-064LY)

This antibody pair set can be used for detecting and quantifying protein level of human ALDH3A1.
See all ALDH3A1 antibodies

Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-ALDH3A1 polyclonal antibody, 100 ug

Detection Antibody

Anti-ALDH3A1 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Alternative Names

Aldehyde Dehydrogenase 3 Family Member A1; Aldehyde Dehydrogenase, Dimeric NADP-Preferring; EC 1.2.1.5; ALDHIII; ALDH3; Aldehyde Dehydrogenase 3 Family, Member A1; Aldehyde Dehydrogenase Family 3 Member A1;

Entrez Gene ID

218

UniProt ID

P30838

References

Suwala, A. K., Koch, K., Rios, D. H., Aretz, P., Uhlmann, C., Ogorek, I., ... & Maciaczyk, J. (2018). Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro. Oncotarget, 9(32), 22703.

Saiki, J. P., Cao, H., Van Wassenhove, L. D., Viswanathan, V., Bloomstein, J., Nambiar, D. K., ... & Mochly-Rosen, D. (2018). Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes. Proceedings of the National Academy of Sciences, 115(24), 6279-6284.

Duong, H. Q., You, K. S., Oh, S., Kwak, S. J., & Seong, Y. S. (2017). Silencing of NRF2 reduces the expression of ALDH1A1 and ALDH3A1 and sensitizes to 5-FU in pancreatic cancer cells. Antioxidants, 6(3), 52.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Alternative Versions

ALDH3A1 Matched Antibody Pair (063)

Antibody Pairs

ALDH3A1 Matched Antibody Pair (063)

Related Products

ALDH3A1 Matched Antibody Pair (063)

Rabbit Anti-ALDH3A1 Recombinant Antibody (BA0332)

Mouse Anti-ALDH3A1 Recombinant Antibody (G2)

Mouse Anti-ALDH3A1 Recombinant Antibody (B8)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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