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Rabbit Anti-ALDH3A1 Recombinant Antibody (BA0332) (CBMAB-0058CQ)

This product is a rabbit antibody that recognizes ALDH3A1. The antibody BA0332 can be used for immunoassay techniques such as: WB, FC.
See all ALDH3A1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
BA0332
Antibody Isotype
IgG
Application
WB, ELISA

Basic Information

Immunogen
Recombinant Human ALDH3A1 Protein.
Host Species
Rabbit
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
ELISA1:5,000-1:10,000
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Aldehyde Dehydrogenase 3 Family Member A1
Introduction
ALDH3A1 (Aldehyde Dehydrogenase 3 Family Member A1) is a Protein Coding gene. Diseases associated with ALDH3A1 include Breast Adenocarcinoma. Among its related pathways are Metabolism and Histidine metabolism. GO annotations related to this gene include oxidoreductase activity and aldehyde dehydrogenase (NAD) activity. Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. ALDH3A1 (Aldehyde Dehydrogenase 3 Family Member A1) is a Protein Coding gene. Diseases associated with ALDH3A1 include Breast Adenocarcinoma. Among its related pathways are Metabolism and Histidine metabolism. GO annotations related to this gene include oxidoreductase activity and aldehyde dehydrogenase (NAD) activity. An important paralog of this gene is ALDH3A2.
Entrez Gene ID
218
UniProt ID
P30838
Alternative Names
Aldehyde Dehydrogenase 3 Family, Member A1; EC 1.2.1.5; ALDHIII; ALDH3; Aldehyde Dehydrogenase Family 3 Member A1; Aldehyde Dehydrogenase Isozyme 3; Aldehyde Dehydrogenase Type III; Stomach Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 3; Dimeric NADP-Preferring; Aldehyde Dehydrogenase; EC 1.2.1
Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).
Biological Process
Aging Source: Ensembl
Cellular aldehyde metabolic process Source: UniProtKB
Positive regulation of cell population proliferation Source: Ensembl
Response to cAMP Source: Ensembl
Response to drug Source: Ensembl
Response to glucocorticoid Source: Ensembl
Response to hypoxia Source: Ensembl
Response to nutrient Source: Ensembl
Xenobiotic metabolic process Source: Reactome
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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