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Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595)

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Tested Data
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in ELISA
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in ELISA
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in WB
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in WB
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in WB
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in WB
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in FC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in IHC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in IHC
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in IF
Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595) in IF
Datasheet
SDS
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
CBT2860
Application
IHC, ICC, FC
Immunogen
Purified recombinant fragment of human CCR10 (AA: extra mix) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
IHC-P1:200-1:1,000
ICC1:200-1:1,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
C-C Motif Chemokine Receptor 10
Entrez Gene ID
2826
UniProt ID
P46092
Function
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-52
Helical: 53-68
Cytoplasmic: 69-78
Helical: 79-99
Extracellular: 100-114
Helical: 115-136
Cytoplasmic: 137-159
Helical: 160-179
Extracellular: 180-203
Helical: 204-225
Cytoplasmic: 226-247
Helical: 248-269
Extracellular: 270-290
Helical: 291-313
Cytoplasmic: 314-362

Lim, H. D., Lane, J. R., Canals, M., & Stone, M. J. (2021). Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10. International Journal of Molecular Sciences, 22(8), 4232.

Korbecki, J., Grochans, S., Gutowska, I., Barczak, K., & Baranowska-Bosiacka, I. (2020). CC chemokines in a tumor: a review of pro-cancer and anti-cancer properties of receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 ligands. International journal of molecular sciences, 21(20), 7619.

Kawano, Y., Kakoki, M., Inada, Y., Nishimura, N., Okuno, Y., Hata, H., & Matsuoka, M. (2017). Altered Expression of CCR10 Indicates Malignant Transformation of Bone Marrow Plasma Cells. Blood, 130(Supplement 1), 1782-1782.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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