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CCR10

CCR10 (C-C Motif Chemokine Receptor 10) is a Protein Coding gene. Diseases associated with CCR10 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CXCR3.
Full Name
C-C Motif Chemokine Receptor 10
Function
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-52
Helical: 53-68
Cytoplasmic: 69-78
Helical: 79-99
Extracellular: 100-114
Helical: 115-136
Cytoplasmic: 137-159
Helical: 160-179
Extracellular: 180-203
Helical: 204-225
Cytoplasmic: 226-247
Helical: 248-269
Extracellular: 270-290
Helical: 291-313
Cytoplasmic: 314-362

Anti-CCR10 antibodies

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Target: CCR10
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse, Rat
Clone: CBXC-1682
Application*: F
Target: CCR10
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0808
Application*: F
Target: CCR10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-1092
Application*: F
Target: CCR10
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBFYC-0473
Application*: F
Target: CCR10
Host: Hamster
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: 6588-5
Application*: F
Target: CCR10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 314305
Application*: F, MC
Target: CCR10
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse, Rat
Clone: 248918
Application*: F, MC
Target: CCR10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0007
Application*: F, MC
Target: CCR10
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse, Rat
Clone: CBYY-C1129
Application*: F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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