CCR10

CCR10 (C-C Motif Chemokine Receptor 10) is a Protein Coding gene. Diseases associated with CCR10 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CXCR3.
Full Name
C-C Motif Chemokine Receptor 10
Function
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Biological Process
Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 1-52
Helical: 53-68
Cytoplasmic: 69-78
Helical: 79-99
Extracellular: 100-114
Helical: 115-136
Cytoplasmic: 137-159
Helical: 160-179
Extracellular: 180-203
Helical: 204-225
Cytoplasmic: 226-247
Helical: 248-269
Extracellular: 270-290
Helical: 291-313
Cytoplasmic: 314-362
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Anti-CCR10 antibodies

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Target: CCR10
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0808
Application*: F
Target: CCR10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 314305
Application*: F
Target: CCR10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-C1129
Application*: WB, IP, IF, E, P
Target: CCR10
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 248918
Application*: F
Target: CCR10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2285
Application*: F
Target: CCR10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2860
Application*: IH, IC, F
Target: CCR10
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-0473
Application*: WB, IP, IF, E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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