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CCR10

CCR10 (C-C Motif Chemokine Receptor 10) is a Protein Coding gene. Diseases associated with CCR10 include Mycosis Fungoides and Sezary's Disease. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CXCR3.

Full Name

C-C Motif Chemokine Receptor 10

Function

Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.

Biological Process

Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-52
Helical: 53-68
Cytoplasmic: 69-78
Helical: 79-99
Extracellular: 100-114
Helical: 115-136
Cytoplasmic: 137-159
Helical: 160-179
Extracellular: 180-203
Helical: 204-225
Cytoplasmic: 226-247
Helical: 248-269
Extracellular: 270-290
Helical: 291-313
Cytoplasmic: 314-362

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Anti-CCR10 antibodies

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Human Anti-CCR10 Recombinant Antibody (CBXC-0808) (CBMAB-C1922-CQ)

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Target: CCR10

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXC-0808

Application*: F

Rat Anti-CCR10 Recombinant Antibody (314305) (CBMAB-C0949-LY)

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Target: CCR10

Host: Rat

Antibody Isotype: IgG2a

Specificity: Human

Clone: 314305

Application*: F

Mouse Anti-CCR10 Recombinant Antibody (CBYY-C1129) (CBMAB-C2566-YY)

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Target: CCR10

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBYY-C1129

Application*: WB, IP, IF, E, P

Rat Anti-CCR10 Recombinant Antibody (248918) (CBMAB-C0724-LY)

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Target: CCR10

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 248918

Application*: F

Mouse Anti-CCR10 Recombinant Antibody (CBT2285) (V2LY-0625-LY1596)

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Target: CCR10

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT2285

Application*: F

Mouse Anti-CCR10 Recombinant Antibody (CBT2860) (V2LY-0625-LY1595)

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Target: CCR10

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT2860

Application*: IH, IC, F

Mouse Anti-CCR10 Recombinant Antibody (CBFYC-0473) (CBMAB-C0520-FY)

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Target: CCR10

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse, Rat

Clone: CBFYC-0473

Application*: WB, IP, IF, E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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