Human ARHGDIB ELISA Kit (V2LY-0626-LY5182)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0073 ng/mL
Detection Range
0.015-3 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
23.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Rho GDP Dissociation Inhibitor Beta
Function
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369).
Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
Biological Process
Cellular response to redox state Source: Ensembl
Multicellular organism development Source: ProtInc
Negative regulation of cell adhesion Source: ProtInc
Negative regulation of trophoblast cell migration Source: CACAO
Positive regulation of GTPase activity Source: GOC
Regulation of actin cytoskeleton reorganization Source: UniProtKB
Regulation of Rho protein signal transduction Source: UniProtKB
Regulation of small GTPase mediated signal transduction Source: Reactome
Rho protein signal transduction Source: GO_Central
Cellular Location
Cytosol

Betjes, M. G., Sablik, K. A., Litjens, N. H., Otten, H. G., & de Weerd, A. E. (2021). ARHGDIB and AT1R autoantibodies are differentially related to the development and presence of chronic antibody-m

Wang, X., Bi, X., Huang, X., Wang, B., Guo, Q., & Wu, Z. (2020). Systematic investigation of biomarker-like role of ARHGDIB in breast cancer. Cancer Biomarkers, 28(1), 101-110.

Senev, A., Otten, H. G., Kamburova, E. G., Callemeyn, J., Lerut, E., Van Sandt, V., ... & Naesens, M. (2020). Antibodies against ARHGDIB and ARHGDIB gene expression associate with kidney allograft outcome. Transplantation, 104(7), 1462-1471.

Kardol-Hoefnagel, T., van Logtestijn, S. A., & Otten, H. G. (2020). A review on the function and regulation of ARHGDIB/RhoGDI2 expression including the hypothetical role of ARHGDIB/RhoGDI2 autoantibodies in kidney transplantation. Transplantation direct, 6(5).

Kamburova, E. G., Gruijters, M. L., Kardol‐Hoefnagel, T., Wisse, B. W., Joosten, I., Allebes, W. A., ... & Otten, H. G. (2019). Antibodies against ARHGDIB are associated with long‐term kidney graft loss. American Journal of Transplantation, 19(12), 3335-3344.

Cao, L., Lafyatis, R., & Burkly, L. C. (2017). Increased dermal collagen bundle alignment in systemic sclerosis is associated with a cell migration signature and role of Arhgdib in directed fibroblast migration on aligned ECMs. PloS one, 12(6), e0180751.

von Klot, C. A., Dubrowinskaja, N., Peters, I., Hennenlotter, J., Merseburger, A. S., Stenzl, A., ... & Serth, J. (2017). Rho GDP dissociation inhibitor‑β in renal cell carcinoma. Oncology letters, 14(6), 8190-8196.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

ARHGDIB Matched Antibody Pair (102) (CAT#: APMAB-102LY)

ARHGDIB Matched Antibody Pair (103) (CAT#: APMAB-103LY)

Antibody Pairs

ARHGDIB Matched Antibody Pair (102) (CAT#: APMAB-102LY)

ARHGDIB Matched Antibody Pair (103) (CAT#: APMAB-103LY)

Related Products

Mouse Anti-ARHGDIB Recombinant Antibody (CBYC-A758) (CAT#: CBMAB-A3514-YC)

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Mouse Anti-ARHGDIB Recombinant Antibody (8J1255) (CAT#: CBMAB-D0021-YC)

ARHGDIB Matched Antibody Pair (103) (CAT#: APMAB-103LY)

Mouse Anti-ARHGDIB Recombinant Antibody (17) (CAT#: CBMAB-AP436LY)

Mouse Anti-ARHGDIB Recombinant Antibody (2C12-B6) (CAT#: CBMAB-A3513-YC)

ARHGDIB Matched Antibody Pair (102) (CAT#: APMAB-102LY)

Mouse Anti-ARHGDIB Recombinant Antibody (CBYC-A759) (CAT#: CBMAB-A3515-YC)

Mouse Anti-ARHGDIB Recombinant Antibody (10D774) (CAT#: CBMAB-D0022-YC)

Isotype control

For research use only. Not intended for any clinical use.

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