Human Recombinant TCL1A protein, His Tag (V2LY-0526-LY7144)

Name: Human Recombinant TCL1A protein, His Tag
SKU: V2LY-0526-LY7144
Rating: 5 (1 reviews)

See all TCL1A antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

E. coli

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant TCL1A protein, His Tag consist of Amino Acid: 2-114 and predicts a molecular mass of 15.2 kDa.

Molecule Mass

15.2 kDa

Sequence

Amino Acid: 2-114

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>88% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile PBS

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

TCL1A Gene(Protein Coding) T Cell Leukemia/Lymphoma 1A

Function

Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.

Biological Process

Biological Process cellular response to tumor necrosis factorIDA:UniProtKB1 Publication
Biological Process negative regulation of apoptotic processIDA:UniProtKB1 Publication
Biological Process positive regulation of cell population proliferationIDA:UniProtKB1 Publication
Biological Process positive regulation of mitochondrial membrane potentialIDA:UniProtKB1 Publication
Biological Process positive regulation of peptidyl-serine phosphorylationIMP:UniProtKB1 Publication
Biological Process positive regulation of protein serine/threonine kinase activityIDA:UniProtKB1 Publication
Biological Process positive regulation of protein-containing complex assemblyIDA:UniProtKB1 Publication

Cellular Location

Cytoplasm
Nucleus
Microsome
Endoplasmic reticulum
Microsomal fraction.

Involvement in disease

Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Human Recombinant TCL1A protein, His Tag?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

TCL1A Matched Antibody Pair (1192) (CAT#: APMAB-1192LY)

Antibody Pairs

TCL1A Matched Antibody Pair (1192) (CAT#: APMAB-1192LY)

Related Products

Mouse Anti-TCL1A Recombinant Antibody (1-21) (CAT#: CBMAB-CP2725-LY)

Mouse Anti-TCL1A Recombinant Antibody (1C4) (CAT#: CBMAB-A8973-LY)

TCL1A Matched Antibody Pair (1192) (CAT#: APMAB-1192LY)

Mouse Anti-TCL1A Recombinant Antibody (CBYJT-2309) (CAT#: CBMAB-T1419-YJ)

Mouse Anti-TCL1A Recombinant Antibody (CBYJT-2312) (CAT#: CBMAB-T1422-YJ)

Mouse Anti-TCL1A Recombinant Antibody (CBYJT-2311) (CAT#: CBMAB-T1421-YJ)

Mouse Anti-TCL1A Recombinant Antibody (2F7) (CAT#: CBMAB-A8977-LY)

Mouse Anti-TCL1A Recombinant Antibody (2D7) (CAT#: CBMAB-A8975-LY)

Mouse Anti-TCL1A Recombinant Antibody (CBYJT-2308) (CAT#: CBMAB-T1418-YJ)

Mouse Anti-TCL1A Recombinant Antibody (2F1) (CAT#: CBMAB-A8976-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry