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Mouse Anti-TCL1A Recombinant Antibody (1-21) (CBMAB-CP2725-LY)

The product is antibody recognizes TCL1A. The antibody 1-21 immunoassay techniques such as: WB,IP.
Host Species
Mouse
Application
WB, IP
Immunogen
Monoclonal antibody is produced by immunizing animals with TCL1.
Antibody Isotype
IgG2b
Specificity
Human, Monkey
Clone
1-21
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
Alternative Name
T Cell Leukemia/Lymphoma 1A; T-Cell Leukemia/Lymphoma 1A; Protein P14 TCL1; Oncogene TCL-1; Oncogene TCL1; TCL1; T-Cell Leukemia/Lymphoma Protein 1A; T-Cell Lymphoma-1;
Entrez Gene ID
UniProt ID
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For Research Use Only. Not For Clinical Use.
Cat CBMAB-CP2725-LY
Conjugates
Size
Price $
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Second antibody and isotype control