Human TMEFF2 ELISA Kit (V2LY-0626-LY3612)

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Tested Data
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Basic Information

Sensitivity
0.0092 ng/mL
Detection Range
0.02-3.8 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
41.4 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
transmembrane protein with EGF-like and two follistatin-like domains 2
Function
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
Biological Process
Biological Process animal organ morphogenesisSource:GO_Central1 Publication
Biological Process cell migrationSource:GO_Central1 Publication
Biological Process negative regulation of cell migrationSource:MGI1 Publication
Biological Process negative regulation of integrin biosynthetic processSource:MGI1 Publication
Biological Process negative regulation of stress fiber assemblySource:MGI1 Publication
Biological Process substrate adhesion-dependent cell spreadingSource:GO_Central1 Publication
Biological Process tissue developmentSource:GO_Central1 Publication
Biological Process wound healing, spreading of cellsSource:MGI1 Publication
Cellular Location
Isoform 1
Membrane
Isoform 2
Membrane
Isoform 3
Secreted
Topology
Extracellular: 41-320
Helical: 321-341
Cytoplasmic: 342-374
PTM
N-glycosylated. Contains chondroitin sulfate glycosaminoglycans.
A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or pro-inflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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