ANXA8
ANXA8 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene h
Full Name
Annexin A8
Function
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Biological Process
Blood coagulation Source: UniProtKB-KW
Endosomal transport Source: UniProtKB
Endosome organization Source: UniProtKB
Negative regulation of phospholipase A2 activity Source: UniProtKB
Negative regulation of serine-type endopeptidase activity Source: UniProtKB
Endosomal transport Source: UniProtKB
Endosome organization Source: UniProtKB
Negative regulation of phospholipase A2 activity Source: UniProtKB
Negative regulation of serine-type endopeptidase activity Source: UniProtKB
Cellular Location
Cytosol; Late endosome membrane; Plasma membrane; Collagen-containing extracellular matrix; Cytoplasm
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Anti-ANXA8 antibodies
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Target: ANXA8
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: C-11
Application*: WB, IP, IF, E
Target: ANXA8
Expressed Host: E. coli
Sequence: Amino Acid: 1-327
Tag: His Tag
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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