ATOX1

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
Full Name
Antioxidant 1 Copper Chaperone
Function
Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.
Biological Process
Cellular copper ion homeostasis Source: GO_Central
Copper ion transport Source: UniProtKB
Response to oxidative stress Source: GO_Central
Cellular Location
Cytosol
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Anti-ATOX1 antibodies

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Mouse Anti-ATOX1 Recombinant Antibody (S65-37) (CBMAB-AP502LY)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: S65-37
Application*: IC/IF, WB
Datasheet SDS

Mouse Anti-ATOX1 Recombinant Antibody (S76-8) (CBMAB-AP501LY)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: S76-8
Application*: IC, IF, IH, IP, WB
Datasheet SDS

Mouse Anti-ATOX1 Recombinant Antibody (3A13) (CBMAB-A0602-LY)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3A13
Application*: WB, E
Datasheet SDS

Human Recombinant ATOX1 protein, His Tag (V2LY-0526-LY2198)

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Target: ATOX1
Expressed Host: E. coli
Sequence: Amino Acid: 1-68
Tag: His Tag
Datasheet SDS

Mouse Anti-ATOX1 Antibody (3E1) (CBMAB-0016-YC)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3E1
Application*: WB
Datasheet SDS

Mouse Anti-ATOX1 Antibody (3B7) (CBMAB-0014-YC)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B7
Application*: WB
Datasheet SDS

Mouse Anti-ATOX1 Antibody (2E6) (CBMAB-0011-YC)

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Target: ATOX1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2E6
Application*: WB, E, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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