BCAT1

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. [provided by RefSeq]
Full Name
branched chain aminotransferase 1, cytosolic
Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Biological Process
Branched-chain amino acid biosynthetic process Source: ProtInc
Branched-chain amino acid catabolic process Source: Reactome
G1/S transition of mitotic cell cycle Source: ProtInc
Leucine biosynthetic process Source: GO_Central
Valine biosynthetic process Source: GO_Central
Cellular Location
Cytoplasm
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Anti-BCAT1 antibodies

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Mouse Anti-BCAT1 Recombinant Antibody (CBYY-0294) (CBMAB-0295-YY)

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Target: BCAT1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0294
Application*: E, WB
Datasheet SDS

Mouse Anti-BCAT1 Recombinant Antibody (3F5) (CBMAB-1196-CN)

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Target: BCAT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Monkey, Cat
Clone: 3F5
Application*: WB, IH
Datasheet SDS

Mouse Anti-BCAT1 Recombinant Antibody (1F8) (CBMAB-1195-CN)

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Target: BCAT1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1F8
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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