CCL13

CCL13 (C-C Motif Chemokine Ligand 13) is a Protein Coding gene. Diseases associated with CCL13 include Allergic Hypersensitivity Disease and Asthma. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CCL2.
Full Name
C-C Motif Chemokine Ligand 13
Function
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell-cell signaling Source: ProtInc
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
Cytoskeleton organization Source: UniProtKB
Eosinophil chemotaxis Source: UniProtKB
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Regulation of cell shape Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Secreted
PTM
One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain.
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Anti-CCL13 antibodies

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Mouse Anti-CCL13 Recombinant Antibody (73506) (CBMAB-C8441-LY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 73506
Application*: F, N, E
Functional Assay
Datasheet SDS

Human CCL13 ELISA Kit (V2LY-0626-LY289)

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Target: CCL13
Sensitivity: 0.0096 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Human Recombinant CCL13 protein, His Tag (V2LY-0526-LY5482)

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Target: CCL13
Expressed Host: Yeast
Sequence: Amino Acid: 24-98
Tag: His Tag
Datasheet SDS

Mouse Anti-CCL13 Recombinant Antibody (CBFYC-0926) (CBMAB-C0982-FY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-0926
Application*: N, WB
Functional Assay
Datasheet SDS

Mouse Anti-CCL13 Recombinant Antibody (CBFYM-0903) (CBMAB-M1051-FY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0903
Application*: E
Datasheet SDS

Mouse Anti-CCL13 Recombinant Antibody (CBFYM-0902) (CBMAB-M1050-FY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0902
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL13 Recombinant Antibody (CBFYM-0901) (CBMAB-M1049-FY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0901
Application*: E, WB
Datasheet SDS

Mouse Anti-CCL13 Recombinant Antibody (CBFYM-0210) (CBMAB-M0252-FY)

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Target: CCL13
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYM-0210
Application*: WB, IP, IF, E, P
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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