DHX29

This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016]
Full Name
DExH-Box Helicase 29
Function
ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
Biological Process
Formation of translation preinitiation complex Source: CACAO
Positive regulation of translational initiation Source: UniProtKB-UniRule
Ribosome assembly Source: CACAO
Cellular Location
Cytoplasm
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Anti-DHX29 antibodies

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Mouse Anti-DHX29 Recombinant Antibody (D0850) (V2LY-0425-LY288)

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Target: DHX29
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: D0850
Application*: IP, WB, F
Datasheet SDS

Mouse Anti-DHX29 Recombinant Antibody (D0849) (V2LY-0425-LY287)

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Target: DHX29
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: D0849
Application*: WB, IP, IF, E
Datasheet SDS

Rabbit Anti-DHX29 Recombinant Antibody (D19E10) (CBMAB-D0850-YC)

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Target: DHX29
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D19E10
Application*: IP, WB
Datasheet SDS

Mouse Anti-DHX29 Recombinant Antibody (2269C1) (CBMAB-D0849-YC)

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Target: DHX29
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2269C1
Application*: DB, F, IC, IP, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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