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DSG3

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
Full Name
Desmoglein 3
Research Area
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Biological Process
Cell-cell adhesion Source: GO_Central
Homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
Cellular Location
Cell membrane; Desmosome
Topology
Extracellular: 50-615
Helical: 616-640
Cytoplasmic: 641-999
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Anti-DSG3 antibodies

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Mouse Anti-DSG3 Recombinant Antibody (18) (CBMAB-D1789-YC)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 18
Application*: F
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (CBT2671) (V2LY-0625-LY80)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2671
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (CBT4276) (V2LY-0625-LY75)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4276
Application*: WB
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (CBHb197) (V2LY-0425-LY999)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBHb197
Application*: E
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (CBFYA-0126) (V2LY-0425-LY998)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBFYA-0126
Application*: IF, IP, P, WB
Datasheet SDS

Rabbit Anti-DSG3 Recombinant Antibody (CBYCD-425) (V2LY-0425-LY995)

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Target: DSG3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYCD-425
Application*: WB
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (D1781) (V2LY-0425-LY992)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: D1781
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (D1780) (V2LY-0425-LY991)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: D1780
Application*: WB, IF, IP, IH
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (3G133) (V2LY-0425-LY990)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G133
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (4A31) (CBMAB-D1788-YC)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4A31
Application*: IH, E, F, WB
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (6G2C11) (CBMAB-D1783-YC)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6G2C11
Application*: IH, WB
Datasheet SDS

Mouse Anti-DSG3 Recombinant Antibody (5H10) (CBMAB-D1782-YC)

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Target: DSG3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5H10
Application*: WB, IF, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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