FETUB

The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells.

Full Name

Fetuin B

Research Area

Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity).

Biological Process

Binding of sperm to zona pellucida Source: UniProtKB
Negative regulation of endopeptidase activity Source: UniProtKB
Single fertilization Source: UniProtKB

Cellular Location

Secreted

Anti-FETUB antibodies

Mouse Anti-FETUB Recombinant Antibody (CBXF-1659) (CBMAB-F4044-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-1659

Application*: WB

Mouse Anti-FETUB Recombinant Antibody (CBXF-2957) (CBMAB-F3663-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2957

Application*: E

Rabbit Anti-FETUB Recombinant Antibody (CBXF-1867) (CBMAB-F3401-CQ)

Datasheet

SDS

Target: FETUB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBXF-1867

Application*: E

Rabbit Anti-FETUB Recombinant Antibody (CBXF-1866) (CBMAB-F3400-CQ)

Datasheet

SDS

Target: FETUB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-1866

Application*: E

Mouse Anti-FETUB Recombinant Antibody (CBXF-2602) (CBMAB-F3033-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2602

Application*: ED

Mouse Anti-FETUB Recombinant Antibody (CBXF-2151) (CBMAB-F1636-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2151

Application*: WB

Mouse Anti-FETUB Recombinant Antibody (CBXF-0508) (CBMAB-F1436-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-0508

Application*: WB, IC, P, C, E

Rabbit Anti-FETUB Recombinant Antibody (CBXF-3507) (CBMAB-F1317-CQ)

Datasheet

SDS

Target: FETUB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-3507

Application*: E

Rabbit Anti-FETUB Recombinant Antibody (CBXF-3505) (CBMAB-F1174-CQ)

Datasheet

SDS

Target: FETUB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBXF-3505

Application*: E, WB

Rabbit Anti-FETUB Recombinant Antibody (CBXF-1138) (CBMAB-F0847-CQ)

Datasheet

SDS

Target: FETUB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Rat, Human

Clone: CBXF-1138

Application*: WB, P

Mouse Anti-FETUB (AA 19-362) Recombinant Antibody (CBXF-0507) (CBMAB-F0286-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0507

Application*: E

Mouse Anti-FETUB Recombinant Antibody (CBXF-2604) (CBMAB-F0130-CQ)

Datasheet

SDS

Target: FETUB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2604

Application*: WB, EC

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)