GSPT2

This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010]
Full Name
G1 To S Phase Transition 2
Function
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Biological Process
Cell cycle Source: UniProtKB-KW
Cytoplasmic translational termination Source: GO_Central
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: UniProtKB-KW
Translation Source: GO_Central
Cellular Location
Cytoplasm
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Anti-GSPT2 antibodies

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Mouse Anti-GSPT2 Recombinant Antibody (CBLG1-2998) (CBMAB-G5305-LY)

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Target: GSPT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-2998
Application*: WB
Datasheet SDS

Mouse Anti-GSPT2 Recombinant Antibody (CBFYE-1456) (CBMAB-E2084-FY)

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Target: GSPT2
Host: Mouse
Specificity: Human
Clone: CBFYE-1456
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-GSPT2 Recombinant Antibody (CBFYE-1455) (CBMAB-E2083-FY)

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Target: GSPT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYE-1455
Application*: WB, F, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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