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Mouse Anti-GSPT2 Recombinant Antibody (CBFYE-1455) (CBMAB-E2083-FY)

This product is mouse antibody that recognizes GSPT2. The antibody CBFYE-1455 can be used for immunoassay techniques such as: WB, FC, IF.
See all GSPT2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-1455
Antibody Isotype
IgG1
Application
WB, FC, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.32 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
G1 To S Phase Transition 2
Introduction
This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.
Entrez Gene ID
23708
UniProt ID
Q8IYD1
Alternative Names
G1 To S Phase Transition 2; Eukaryotic Peptide Chain Release Factor Subunit 3b; ERF3B; Eukaryotic Peptide Chain Release Factor GTP-Binding Subunit ERF3B; G1 To S Phase Transition Protein 2 Homolog; GST2
Function
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Biological Process
Cell cycle Source: UniProtKB-KW
Cytoplasmic translational termination Source: GO_Central
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: UniProtKB-KW
Translation Source: GO_Central
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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