ICAM5

ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. It is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Full Name
Intercellular Adhesion Molecule 5
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Biological Process
Cell adhesion Source: GO_Central
Cell-cell adhesion Source: InterPro
Phagocytosis Source: Ensembl
Cellular Location
Membrane
Topology
Extracellular: 32-835
Helical: 836-856
Cytoplasmic: 857-924
PTM
Glycosylation at Asn-54 is critical for functional folding.
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Anti-ICAM5 antibodies

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Mouse Anti-ICAM5 Recombinant Antibody (21/CD51) (CBMAB-C0593-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat, Dog, Mouse
Clone: 21/CD51
Application*: WB, IF
Datasheet SDS

Human Recombinant ICAM5 protein, hFc Tag (V2LY-0526-LY4632)

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Target: ICAM5
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-132
Tag: hFc Tag
Datasheet SDS

Human Recombinant ICAM5 protein, ECD, His Tag (V2LY-0526-LY4631)

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Target: ICAM5
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-834
Tag: His Tag
Datasheet SDS

Human Recombinant ICAM5 protein, ECD, hFc Tag (V2LY-0526-LY4630)

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Target: ICAM5
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-570
Tag: hFc Tag
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (CBYJT-1386) (CBMAB-T0408-YJ)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1386
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (CBYY-I0090) (CBMAB-I0229-YY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I0090
Application*: WB, IC
Datasheet SDS

Rat Anti-ICAM5 Recombinant Antibody (CBYY-I0089) (CBMAB-I0228-YY)

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Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0089
Application*: WB
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (7H212) (CBMAB-C8824-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H212
Application*: F
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (2Q888) (CBMAB-C5401-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q888
Application*: F, IF
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (272-17E6) (CBMAB-C4509-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 272-17E6
Application*: E, F, IH, IP
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (23C6) (CBMAB-C4456-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 23C6
Application*: C, FN, F
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (13H175) (CBMAB-C2898-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H175
Application*: F, IF
Datasheet SDS

Mouse Anti-ICAM5 Recombinant Antibody (13C2) (CBMAB-C0313-LY)

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13C2
Application*: C, F
Datasheet SDS

Rat Anti-ICAM5 Monoclonal Antibody (191321) (CBMAB-1354-YC)

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Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 191321
Application*: WB
Datasheet SDS

Rat Anti-ICAM5 Monoclonal Antibody (RM0250-3J37) (CBMAB-1353-YC)

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Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: RM0250-3J37
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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