ICAM5

ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. It is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Full Name
Intercellular Adhesion Molecule 5
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
Biological Process
Cell adhesion Source: GO_Central
Cell-cell adhesion Source: InterPro
Phagocytosis Source: Ensembl
Cellular Location
Membrane
Topology
Extracellular: 32-835
Helical: 836-856
Cytoplasmic: 857-924
PTM
Glycosylation at Asn-54 is critical for functional folding.
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Anti-ICAM5 antibodies

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Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat, Dog, Mouse
Clone: 21/CD51
Application*: WB, IF
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-1386
Application*: WB, IC, P, C, E
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I0090
Application*: WB, IC
Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-I0089
Application*: WB
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H212
Application*: F
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2Q888
Application*: F, IF
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 272-17E6
Application*: E, F, IH, IP
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 23C6
Application*: C, FN, F
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H175
Application*: F, IF
Target: ICAM5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13C2
Application*: C, F
Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 191321
Application*: WB
Target: ICAM5
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: RM0250-3J37
Application*: WB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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