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ITGAX

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Full Name
Integrin Subunit Alpha X
Function
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Biological Process
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Defense response to virusIEA:Ensembl
Heterotypic cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell migrationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of endothelial tube morphogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of myelinationISS:ARUK-UCL
Cellular Location
Membrane
Topology
Extracellular: 20-1107
Helical: 1108-1128
Cytoplasmic: 1129-1163

Anti-ITGAX antibodies

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Human Anti-ITGAX Recombinant Antibody (CBXC-0900) (CBMAB-C2015-CQ)

Datasheet SDS
Target: ITGAX
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0900
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (MJ4-27G12) (CBMAB-C1797-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: MJ4-27G12
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (CBXC-1368) (CBMAB-C1636-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1368
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (CBXC-1242) (CBMAB-C1509-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1242
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (FK24) (CBMAB-C5201WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FK24
Application*: IC, IC

Rabbit Anti-ITGAX Recombinant Antibody (CBWJC-3903) (CBMAB-C5200WJ)

Datasheet SDS
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3903
Application*: WB, IC

Mouse Anti-ITGAX Recombinant Antibody (CBWJC-3900) (CBMAB-C5197WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3900
Application*: WB, IH, P

Mouse Anti-ITGAX Recombinant Antibody (CBR-p150/4G1) (CBMAB-C5196WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBR-p150/4G1
Application*: F, C, FN

Mouse Anti-ITGAX Recombinant Antibody (CA11.6A1) (CBMAB-C5195WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog
Clone: CA11.6A1
Application*: F, IH, IP, C

Mouse Anti-ITGAX Recombinant Antibody (CBWJC-2246) (CBMAB-C3076WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2246
Application*: WB, F, IH

Mouse Anti-ITGAX Recombinant Antibody (CBWJC-2245) (CBMAB-C3072WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2245
Application*: F, IP, MC

Armenian Hamster Anti-ITGAX Recombinant Antibody (CBWJC-2244) (CBMAB-C3071WJ)

Datasheet SDS
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG1, λ
Specificity: Mouse
Clone: CBWJC-2244
Application*: F

Rabbit Anti-ITGAX Recombinant Antibody (CBWJC-2243) (CBMAB-C3069WJ)

Datasheet SDS
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-2243
Application*: WB, IP, P, C, IC

Mouse Anti-ITGAX Recombinant Antibody (CBWJC-2241) (CBMAB-C3066WJ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2241
Application*: F

Armenian Hamster Anti-ITGAX Recombinant Antibody (CBWJC-2240) (CBMAB-C3065WJ)

Datasheet SDS
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJC-2240
Application*: F, IH, IC, IP, C, MC

Mouse Anti-ITGAX Recombinant Antibody (CBXC-2360) (CBMAB-C4630-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2360
Application*: IH

Hamster Anti-ITGAX Recombinant Antibody (CBXC-1454) (CBMAB-C3616-CQ)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXC-1454
Application*: F, IH, IP

Rat Anti-ITGAX Recombinant Antibody (CBXC-1416) (CBMAB-C3615-CQ)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXC-1416
Application*: WB

Rat Anti-ITGAX Recombinant Antibody (CBXC-2517) (CBMAB-C3614-CQ)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-2517
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (3G1) (CBMAB-C6090-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 3G1
Application*: WB, P, IF/IC, IP

Mouse Anti-ITGAX Recombinant Antibody (10B631) (CBMAB-C2261-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 10B631
Application*: F, IH, IP

Rat Anti-ITGAX Recombinant Antibody (223H7) (CBMAB-C0677-LY)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 223H7
Application*: F, IP

Mouse Anti-ITGAX Recombinant Antibody (KB90) (CBMAB-C0758-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KB90
Application*: WB, F, IH, MC

Mouse Anti-ITGAX Recombinant Antibody (ITGAX/1284) (CBMAB-C0746-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: ITGAX/1284
Application*: F, IF, P

Mouse Anti-ITGAX Recombinant Antibody (ITGAX/1242) (CBMAB-C0744-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human
Clone: ITGAX/1242
Application*: F, P, IF

Mouse Anti-ITGAX Recombinant Antibody (HC1/1) (CBMAB-C0685-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HC1/1
Application*: F, IF, IP, C

Armenian Hamster Anti-ITGAX Recombinant Antibody (CBXC-3148) (CBMAB-C0399-CQ)

Datasheet SDS
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-3148
Application*: F, IH, IP, P, MC

Mouse Anti-ITGAX Recombinant Antibody (CBFYC-2833) (CBMAB-C2909-FY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBFYC-2833
Application*: F, IH, IP

Rat Anti-ITGAX Recombinant Antibody (CBFYC-2832) (CBMAB-C2908-FY)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2832
Application*: F

Hamster Anti-ITGAX Recombinant Antibody (CBFYC-2831) (CBMAB-C2907-FY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2831
Application*: P, F, IP

Mouse Anti-ITGAX Recombinant Antibody (CBFYC-2829) (CBMAB-C2905-FY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2829
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (CBFYC-0219) (CBMAB-C0246-FY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0219
Application*: C, IH

Mouse Anti-ITGAX Recombinant Antibody (CBYY-I1622) (CBMAB-I2792-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1622
Application*: F, FN, C, IP

Mouse Anti-ITGAX Recombinant Antibody (CBYY-I1025) (CBMAB-I2193-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1025
Application*: IH

Mouse Anti-ITGAX Recombinant Antibody (CBYY-I0519) (CBMAB-I1185-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: CBYY-I0519
Application*: F, C, IP, IF

Hamster Anti-ITGAX Recombinant Antibody (N418) (CBMAB-I0927-YY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: N418
Application*: F, FN, IH, IF, IP

Mouse Anti-ITGAX (AA 600-850) Recombinant Antibody (CBYY-I0272) (CBMAB-I0763-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human
Clone: CBYY-I0272
Application*: F, IF, P

Hamster Anti-ITGAX Recombinant Antibody (MAB0806) (CBMAB-C9369-LY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: MAB0806
Application*: P, F, IP

Mouse Anti-ITGAX Recombinant Antibody (8A2) (CBMAB-C9034-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 8A2
Application*: F, IF, C, IP

Rat Anti-ITGAX Recombinant Antibody (435421) (CBMAB-C6485-LY)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 435421
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (4ALM2) (CBMAB-EN2029-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4ALM2
Application*: FC, IF

Mouse Anti-ITGAX Recombinant Antibody (CBYY-C0435) (CBMAB-C1391-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0435
Application*: F, IH

Mouse Anti-ITGAX Recombinant Antibody (CBYY-C0597) (CBMAB-C1878-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0597
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (CBYY-C2761) (CBMAB-C4202-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-C2761
Application*: WB, P, IF, IP

Mouse Anti-ITGAX Recombinant Antibody (CBYY-C2762) (CBMAB-C4203-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2762
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (CBYY-C2763) (CBMAB-C4204-YY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2763
Application*: E, WB

Rat Anti-ITGAX Recombinant Antibody (CBYY-C2764) (CBMAB-C4205-YY)

Datasheet SDS
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-C2764
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (CD11C-100/D2) (CBMAB-C0531-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CD11C-100/D2
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (BU15) (CBMAB-C0442-CQ)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BU15
Application*: F, IH, IP, C, MC

Recombinant Mouse Anti-ITGAX Recombinant Antibody (100/D2) (CBMAB-XB0657-YC)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 100/D2
Application*: IP, WB

Mouse Anti-ITGAX Recombinant Antibody (S-HCL-3) (CBMAB-C11851-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: S-HCL-3
Application*: F

Hamster Anti-ITGAX Recombinant Antibody (AP-MAB0806) (CBMAB-C11847-LY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG2
Specificity: Mouse
Clone: AP-MAB0806
Application*: F

Hamster Anti-ITGAX Recombinant Antibody (AP-MAB0814) (CBMAB-C11848-LY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: AP-MAB0814
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (MM0422-3J16) (CBMAB-C11856-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0422-3J16
Application*: WB, F

Hamster Anti-ITGAX Recombinant Antibody (MAB0814) (CBMAB-C11855-LY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: MAB0814
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (3A1) (CBMAB-A4582-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3A1
Application*: WB, E

Rabbit Anti-ITGAX Recombinant Antibody (D1V9Y) (CBMAB-CP1235-LY)

Datasheet SDS
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D1V9Y
Application*: WB, IH, P, IF, IF (IC)

Mouse Anti-ITGAX Recombinant Antibody (3.9) (CBMAB-BR318LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3.9
Application*: FC

Mouse Anti-ITGAX Recombinant Antibody (CF249) (CBMAB-FT390LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF249
Application*: ELISA, WB, IHC

Mouse Anti-ITGAX Recombinant Antibody (CAP910) (CBMAB-AP2778LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP910
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (235) (CBMAB-AP2783LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 235
Application*: ELISA, IHC, WB

Hamster Anti-ITGAX Recombinant Antibody (A685) (CBMAB-AP15770LY)

Datasheet SDS
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: A685
Application*: FC, IF, IHC, IP

Mouse Anti-ITGAX Recombinant Antibody (A686) (CBMAB-AP10931LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A686
Application*: IF, IHC, IP, WB

Mouse Anti-ITGAX Recombinant Antibody (4A3.9) (CBMAB-EN2028-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4A3.9
Application*: FC, IF

Mouse Anti-ITGAX Recombinant Antibody (118/A5) (CBMAB-C0220-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 118/A5
Application*: C, P

Anti-ITGAX Recombinant Antibody (3.9) (CBMAB-C0920-LY)

Datasheet SDS
Target: ITGAX
Antibody Isotype: IgG
Specificity: Human
Clone: 3.9
Application*: F, C

Mouse Anti-ITGAX Recombinant Antibody (3J16) (CBMAB-C6391-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3J16
Application*: WB

Mouse Anti-ITGAX Recombinant Antibody (428CT12.2.6.4) (CBMAB-C6475-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 428CT12.2.6.4
Application*: E, WB

Mouse Anti-ITGAX Recombinant Antibody (CAP1041) (CBMAB-AP2777LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CAP1041
Application*: IP, WB

Mouse Anti-ITGAX Recombinant Antibody (8E3) (CBMAB-C9159-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 8E3
Application*: C, WB

Mouse Anti-ITGAX Recombinant Antibody (7H115) (CBMAB-C8758-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H115
Application*: F

Mouse Anti-ITGAX Recombinant Antibody (5K216) (CBMAB-C7778-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5K216
Application*: F, IH

Mouse Anti-ITGAX Recombinant Antibody (3G7-B10) (CBMAB-Z0107-LY)

Datasheet SDS
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G7-B10
Application*: F
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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