ITGAX
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Full Name
Integrin Subunit Alpha X
Alternative Names
Integrin Subunit Alpha X
Function
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
Biological Process
Animal organ morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Defense response to virusIEA:Ensembl
Heterotypic cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell migrationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of endothelial tube morphogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of myelinationISS:ARUK-UCL
Cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Defense response to virusIEA:Ensembl
Heterotypic cell-cell adhesionManual Assertion Based On ExperimentIMP:UniProtKB
Integrin-mediated signaling pathwayIEA:UniProtKB-KW
Positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell migrationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of cell population proliferationManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of endothelial tube morphogenesisManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:ARUK-UCL
Positive regulation of myelinationISS:ARUK-UCL
Cellular Location
Membrane
Topology
Extracellular: 20-1107
Helical: 1108-1128
Cytoplasmic: 1129-1163
Helical: 1108-1128
Cytoplasmic: 1129-1163
View more
Anti-ITGAX antibodies
+ Filters
Loading...
CompareTarget: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: AP-MAB0814
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: MJ4-27G12
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 118/A5
Application*: C, P
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AG122
Application*: B, MC, F, WB
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: AG123
Application*: B, MC, C, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4ALM2
Application*: FC, IF
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4A3.9
Application*: FC, IF
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: A686
Application*: IF, IHC, IP, WB
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: A685
Application*: FC, IF, IHC, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: 235
Application*: ELISA, IHC, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP910
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CAP1041
Application*: IP, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3.9
Application*: FC
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: D1V9Y
Application*: WB, IH, P, IF, IF (IC)
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3A1
Application*: WB, E
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: MAB0814
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MM0422-3J16
Application*: WB, F
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG2
Specificity: Mouse
Clone: AP-MAB0806
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: S-HCL-3
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FK24
Application*: IC, IC
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3903
Application*: WB, IC
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3900
Application*: WB, IH, P
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBR-p150/4G1
Application*: F, C, FN
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog
Clone: CA11.6A1
Application*: F, IH, IP, C
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2246
Application*: WB, F, IH
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2245
Application*: F, IP, MC
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG1, λ
Specificity: Mouse
Clone: CBWJC-2244
Application*: F
Target: ITGAX
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-2243
Application*: WB, IP, P, C, IC
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2241
Application*: F
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBWJC-2240
Application*: F, IH, IC, IP, C, MC
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 100/D2
Application*: IP, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2360
Application*: IH
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBXC-1454
Application*: F, IH, IP
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXC-1416
Application*: WB
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-2517
Application*: F
Target: ITGAX
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0900
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1368
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1242
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KB90
Application*: WB, F, IH, MC
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: ITGAX/1284
Application*: F, IF, P
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human
Clone: ITGAX/1242
Application*: F, P, IF
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HC1/1
Application*: F, IF, IP, C
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CD11C-100/D2
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: BU15
Application*: F, IH, IP, C, MC
Target: ITGAX
Host: Armenian Hamster
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBXC-3148
Application*: F, IH, IP, P, MC
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-C2764
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2763
Application*: E, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2762
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-C2761
Application*: WB, P, IF, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0597
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBFYC-2833
Application*: F, IH, IP
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2832
Application*: F
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2831
Application*: P, F, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2829
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYC-0219
Application*: C, IH
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1622
Application*: F, FN, C, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-I1025
Application*: IH
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: CBYY-I0519
Application*: F, C, IP, IF
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: N418
Application*: F, FN, IH, IF, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG, κ
Specificity: Human
Clone: CBYY-I0272
Application*: F, IF, P
Target: ITGAX
Host: Hamster
Antibody Isotype: IgG
Specificity: Mouse
Clone: MAB0806
Application*: P, F, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 8A2
Application*: F, IF, C, IP
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 435421
Application*: WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 3G1
Application*: WB, P, IF/IC, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: 10B631
Application*: F, IH, IP
Target: ITGAX
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 223H7
Application*: F, IP
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 8E3
Application*: C, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H115
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5K216
Application*: F, IH
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 428CT12.2.6.4
Application*: E, WB
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3J16
Application*: WB
Target: ITGAX
Antibody Isotype: IgG
Specificity: Human
Clone: 3.9
Application*: F, C
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2040
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF249
Application*: ELISA, WB, IHC
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3G7-B10
Application*: F
Target: ITGAX
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0435
Application*: F, IH
More Infomation
Hot products 
-
Mouse Anti-BrdU Recombinant Antibody (IIB5) (CBMAB-1038CQ)
-
Mouse Anti-EMP3 Recombinant Antibody (CBFYE-0100) (CBMAB-E0207-FY)
-
Mouse Anti-AKR1B1 Antibody (V2-2449) (CBMAB-1001CQ)
-
Mouse Anti-ATP1A2 Recombinant Antibody (M7-PB-E9) (CBMAB-A4013-YC)
-
Human Anti-SARS-CoV-2 S1 Monoclonal Antibody (CBFYR-0120) (CBMAB-R0120-FY)
-
Mouse Anti-CAPZB Recombinant Antibody (CBYY-C0944) (CBMAB-C2381-YY)
-
Mouse Anti-BRCA2 Recombinant Antibody (CBYY-1728) (CBMAB-2077-YY)
-
Rabbit Anti-BAD (Phospho-Ser136) Recombinant Antibody (CAP219) (CBMAB-AP536LY)
-
Mouse Anti-ALB Recombinant Antibody (V2-363290) (CBMAB-S0173-CQ)
-
Mouse Anti-ARHGAP5 Recombinant Antibody (54/P190-B) (CBMAB-P0070-YC)
-
Mouse Anti-ARID3A Antibody (A4) (CBMAB-0128-YC)
-
Rabbit Anti-B2M Recombinant Antibody (CBYY-0059) (CBMAB-0059-YY)
-
Mouse Anti-BMI1 Recombinant Antibody (CBYC-P026) (CBMAB-P0108-YC)
-
Mouse Anti-CCDC6 Recombinant Antibody (CBXC-0106) (CBMAB-C5397-CQ)
-
Mouse Anti-F11R Recombinant Antibody (402) (CBMAB-0026-WJ)
-
Mouse Anti-BPGM Recombinant Antibody (CBYY-1806) (CBMAB-2155-YY)
-
Rat Anti-CD34 Recombinant Antibody (MEC 14.7) (CBMAB-C10196-LY)
-
Mouse Anti-CD24 Recombinant Antibody (HIS50) (CBMAB-C10123-LY)
-
Mouse Anti-Acetyl-α-Tubulin (Lys40) Recombinant Antibody (V2-623485) (CBMAB-CP2897-LY)
-
Mouse Anti-8-oxoguanine Recombinant Antibody (V2-7719) (CBMAB-1898CQ)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
Online Inquiry