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LPAR5

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.

Full Name

lysophosphatidic acid receptor 5

Function

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.

Biological Process

Behavioral response to painManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of CREB transcription factor activityManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-26
Helical: 27-47
Cytoplasmic: 48-55
Helical: 56-76
Extracellular: 77-96
Helical: 97-117
Cytoplasmic: 118-136
Helical: 137-157
Extracellular: 158-187
Helical: 188-208
Cytoplasmic: 209-239
Helical: 240-260
Extracellular: 261-276
Helical: 277-297
Cytoplasmic: 298-372

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Anti-LPAR5 antibodies

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Rabbit Anti-LPAR5 Recombinant Antibody (EG1411) (CBMAB-EN1690-LY)

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Target: LPAR5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1411

Application*: WB: 1:500~1:1000 ELISA: 1:1000

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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