LPAR5

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.

Full Name

lysophosphatidic acid receptor 5

Function

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.

Biological Process

Behavioral response to painManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of CREB transcription factor activityManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cell membrane

Topology

Extracellular: 1-26
Helical: 27-47
Cytoplasmic: 48-55
Helical: 56-76
Extracellular: 77-96
Helical: 97-117
Cytoplasmic: 118-136
Helical: 137-157
Extracellular: 158-187
Helical: 188-208
Cytoplasmic: 209-239
Helical: 240-260
Extracellular: 261-276
Helical: 277-297
Cytoplasmic: 298-372

Anti-LPAR5 antibodies

Rabbit Anti-LPAR5 Recombinant Antibody (EG1411) (CBMAB-EN1690-LY)

Datasheet

SDS

Target: LPAR5

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1411

Application*: WB: 1:500~1:1000 ELISA: 1:1000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)