MAP4K3
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Full Name
Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3
Function
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Biological Process
Intracellular signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
JNK cascadeManual Assertion Based On ExperimentTAS:ProtInc
Protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Response to tumor necrosis factorManual Assertion Based On ExperimentIDA:UniProtKB
Response to UVManual Assertion Based On ExperimentIDA:UniProtKB
JNK cascadeManual Assertion Based On ExperimentTAS:ProtInc
Protein phosphorylationManual Assertion Based On ExperimentIDA:UniProtKB
Response to tumor necrosis factorManual Assertion Based On ExperimentIDA:UniProtKB
Response to UVManual Assertion Based On ExperimentIDA:UniProtKB
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Anti-MAP4K3 antibodies
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Target: MAP4K3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A997
Application*: IHC, WB
Target: MAP4K3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBAb160
Application*: WB, IH
Target: MAP4K3
Host: Rabbit
Specificity: Human, Monkey
Clone: CBFYM-1551
Application*: WB, IP
Target: MAP4K3
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBFYM-1550
Application*: WB, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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