PANX2

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Full Name
pannexin 2
Function
Structural component of the gap junctions and the hemichannels.
Biological Process
Cation transportManual Assertion Based On ExperimentIBA:GO_Central
Cell-cell signalingManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of interleukin-1 productionIEA:InterPro
Response to ischemiaIEA:Ensembl
Cellular Location
Cell membrane
Cell junction, gap junction
Topology
Cytoplasmic: 11-47
Helical: 48-70
Extracellular: 71-123
Helical: 124-146
Cytoplasmic: 147-226
Helical: 227-249
Extracellular: 250-292
Helical: 293-315
Cytoplasmic: 316-643
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Anti-PANX2 antibodies

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Mouse Anti-PANX2 Recombinant Antibody (S121A-31) (CBMAB-P0741-YC)

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Target: PANX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: S121A-31
Application*: WB, P
Datasheet SDS

Mouse Anti-PANX2 Recombinant Antibody (2B11) (CBMAB-P0738-YC)

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Target: PANX2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2B11
Application*: WB, IP, E
Datasheet SDS

Mouse Anti-PANX2 Recombinant Antibody (12K156) (CBMAB-P0737-YC)

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Target: PANX2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 12K156
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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