STEAP1
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
Full Name
six transmembrane epithelial antigen of the prostate 1
Function
Metalloreductase that has the ability to reduce both Fe3+ to Fe2+ and Cu2+ to Cu1+. Uses NAD+ as acceptor.
Biological Process
Biological Process ion transportIEA:UniProtKB-KW
Biological Process iron ion homeostasisIEA:UniProtKB-KW
Biological Process iron ion homeostasisIEA:UniProtKB-KW
Cellular Location
Endosome membrane
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Anti-STEAP1 antibodies
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Target: STEAP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: D8B2V
Application*: WB, IP
Target: STEAP1
Host: Mouse
Specificity: Human
Clone: CBXS-3231
Application*: E, WB
Target: STEAP1
Host: Mouse
Specificity: Human
Clone: CBXS-2650
Application*: E, IF, IH, WB
Target: STEAP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: CBXS-2497
Application*: E, IF, IH, WB
Target: STEAP1
Host: Mouse
Specificity: Human
Clone: CBXS-2296
Application*: WB, IP, IF, E
Target: STEAP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-0774
Application*: E, IF, WB
Target: STEAP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBXS-0773
Application*: WB, IP
Target: STEAP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-0772
Application*: E, WB
Target: STEAP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXS-0771
Application*: E, WB, P
Target: STEAP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: J2D2
Application*: WB, E, IH, IF, P
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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