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THAP5

THAP5 (THAP Domain Containing 5) has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952). It may be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).

Full Name

THAP5

Function

Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952).
May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).

Biological Process

Biological Process cell cycleSource:UniProtKB-KW
Biological Process negative regulation of cell cycleSource:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase IISource:ARUK-UCL1 Publication

Cellular Location

Nucleus

PTM

Cleaved by HTRA2 during apoptosis.

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Anti-THAP5 antibodies

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Mouse Anti-THAP5 Recombinant Antibody (CBYJT-2908) (CBMAB-T2143-YJ)

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Target: THAP5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-2908

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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