THAP5

THAP5 (THAP Domain Containing 5) has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952). It may be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).

Full Name

THAP5

Function

Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952).
May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).

Biological Process

Biological Process cell cycleSource:UniProtKB-KW
Biological Process negative regulation of cell cycleSource:UniProtKB1 Publication
Biological Process negative regulation of transcription by RNA polymerase IISource:ARUK-UCL1 Publication

Cellular Location

Nucleus

PTM

Cleaved by HTRA2 during apoptosis.

Anti-THAP5 antibodies

Mouse Anti-THAP5 Recombinant Antibody (CBYJT-2908) (CBMAB-T2143-YJ)

Datasheet

SDS

Target: THAP5

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-2908

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)