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BRD3

This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008]
Full Name
Bromodomain Containing 3
Function
Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors (PubMed:18406326, PubMed:27105114).
Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity).
Biological Process
Chromatin organization Source: UniProtKB-KW
Regulation of transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Nucleus. Detected on chromatin.
Involvement in disease
A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUTM1 which produces a BRD3-NUTM1 fusion protein.
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Anti-BRD3 antibodies

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Rabbit Anti-BRD3 Recombinant Antibody (CBR069G) (CBMAB-BT008LY)

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Target: BRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: CBR069G
Application*: WB, IP
Datasheet SDS

Mouse Anti-BRD3 Recombinant Antibody (CBYY-0801) (CBMAB-0804-YY)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-0801
Application*: WB, IP, IF, FC
Datasheet SDS

Rabbit Anti-BRD3 Recombinant Antibody (EG411) (CBMAB-EN469-LY)

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Target: BRD3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG411
Application*: WB, IF, IH
Datasheet SDS

BRD3 Matched Antibody Pair (143) (APMAB-143LY)

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Target: BRD3
Specificity: Human
Datasheet SDS

Mouse Anti-BRD3 Recombinant Antibody (7G6) (CBMAB-A0879-LY)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 7G6
Application*: WB, E, IH
Datasheet SDS

Mouse Anti-BRD3 Recombinant Antibody (6F3) (CBMAB-A0878-LY)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 6F3
Application*: WB, E
Datasheet SDS

Mouse Anti-BRD3 Recombinant Antibody (CBYY-2148) (CBMAB-2497-YY)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-2148
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-BRD3 Recombinant Antibody (CBYY-1779) (CBMAB-2128-YY)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-1779
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-BRD3 Antibody (1C12) (CBMAB-0172-YC)

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Target: BRD3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1C12
Application*: IP, M
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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