CD82

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Full Name
CD82 Molecule
Function
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-11
Helical: 12-32
Extracellular: 33-53
Helical: 54-72
Cytoplasmic: 73-83
Helical: 84-110
Extracellular: 111-228
Helical: 229-250
Cytoplasmic: 251-267
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Anti-CD82 antibodies

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Mouse Anti-CD82 Recombinant Antibody (CBT3368) (V2LY-0625-LY1979)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBT3368
Application*: IH, F
Datasheet SDS

Mouse Anti-CD82 Recombinant Antibody (CBT2028) (V2LY-0625-LY1978)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2028
Application*: WB, IH, F
Datasheet SDS

Mouse Anti-CD82 Recombinant Antibody (C33) (CBMAB-C0479-CQ)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: C33
Application*: WB, F, IH, IF, IP
Datasheet SDS

Rabbit Anti-CD82 Recombinant Antibody (CBFYC-1451) (CBMAB-C1509-FY)

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Target: CD82
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1451
Application*: P
Datasheet SDS

Mouse Anti-CD82 Recombinant Antibody (CBFYC-1450) (CBMAB-C1508-FY)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYC-1450
Application*: E, IF, IP, WB, P
Datasheet SDS

Mouse Anti-CD82 Recombinant Antibody (4F2) (CBMAB-C6923-LY)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4F2
Application*: E
Datasheet SDS

Rabbit Anti-CD82 Recombinant Antibody (071) (CBMAB-C1849-LY)

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Target: CD82
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 071
Application*: E
Datasheet SDS

Mouse Anti-CD82 Recombinant Antibody (01) (CBMAB-C1572-LY)

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Target: CD82
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 01
Application*: P
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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