COMMD3

COMMD3 (COMM Domain Containing 3) is a Protein Coding gene. Among its related pathways are Innate Immune System.

Full Name

COMM domain containing 3

Function

May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).

May down-regulate activation of NF-kappa-B (PubMed:15799966).

Modulates Na+ transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).

Biological Process

Neutrophil degranulation Source: Reactome
Sodium ion transport Source: UniProtKB-KW

Cellular Location

Cytoplasm; Nucleus

Anti-COMMD3 antibodies

Mouse Anti-COMMD3 Recombinant Antibody (2E2) (CBMAB-C4981-LY)

Datasheet

SDS

Target: COMMD3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2E2

Application*: E, IC, IF

Mouse Anti-COMMD3 Recombinant Antibody (CBXC-0523) (CBMAB-C3144-CQ)

Datasheet

SDS

Target: COMMD3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXC-0523

Application*: E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)