EIF2B3

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Full Name
Eukaryotic Translation Initiation Factor 2B Subunit Gamma
Research Area
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Biological Process
Cytoplasmic translational initiation Source: GO_Central
Hippocampus development Source: Ensembl
Oligodendrocyte development Source: UniProtKB
Response to glucose Source: UniProtKB
Response to heat Source: UniProtKB
Response to peptide hormone Source: UniProtKB
T cell receptor signaling pathway Source: UniProtKB
Translational initiation Source: UniProtKB
Cellular Location
Cytosol; Cytoplasm; Eukaryotic translation initiation factor 2B complex; Guanyl-nucleotide exchange factor complex
Involvement in disease
Leukodystrophy with vanishing white matter (VWM):
A leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease is chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident until adolescence or adulthood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy.
View more

Anti-EIF2B3 antibodies

+ Filters
Loading...

Mouse Anti-EIF2B3 Recombinant Antibody (CBT3467) (V2LY-0625-LY1934)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT3467
Application*: WB, IH, IC, F
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0655) (V2LY-0425-LY1662)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBFYE-0655
Application*: WB, P, IF, IP
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0654) (V2LY-0425-LY1661)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0654
Application*: E, IF, WB, IP
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0653) (V2LY-0425-LY1660)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0653
Application*: E, IF, WB, IP
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0652) (V2LY-0425-LY1659)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0652
Application*: E, IF, WB, IP
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0651) (V2LY-0425-LY1658)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBFYE-0651
Application*: E, IF, P, WB, IP
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0655) (CBMAB-E1068-FY)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: CBFYE-0655
Application*: WB, IH, IF, P
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0654) (CBMAB-E1067-FY)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBFYE-0654
Application*: IF, P, IP, WB
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0653) (CBMAB-E1066-FY)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-0653
Application*: WB, IH
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0652) (CBMAB-E1065-FY)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog
Clone: CBFYE-0652
Application*: WB, IH, IF
Datasheet SDS

Mouse Anti-EIF2B3 Recombinant Antibody (CBFYE-0651) (CBMAB-E1064-FY)

Go to compareCompare
Target: EIF2B3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBFYE-0651
Application*: IC, IF, P, IP, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry
Happy Thanksgiving
Happy Thanksgiving close ad