EIF4A1
EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Among its related pathways are Translation Translation regulation by Alpha-1 adrenergic receptors and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is EIF4A2.
Full Name
Eukaryotic Translation Initiation Factor 4A1
Alternative Names
Eukaryotic Translation Initiation Factor 4A1; ATP-Dependent RNA Helicase EIF4A-1; EIF-4A-I; EIF4A-I; EIF4A; DDX2A; Eukaryotic Translation Initiation Factor 4A, Isoform 1;
Research Area
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Biological Process
Cytoplasmic translational initiation Source: GO_Central
Cellular Location
Cytosol; Extracellular exosome; Cytoplasm; Eukaryotic translation initiation factor 4F complex; Membrane
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Anti-EIF4A1 antibodies
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Target: EIF4A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7C3
Application*: E, WB, IF
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 30E9
Application*: E, WB, IH, IF
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBT33
Application*: WB, P, IF, IC
Target: EIF4A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYE-0696
Application*: WB, IF, F
Target: EIF4A1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYE-0693
Application*: WB, P, IF, F
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: EC138
Application*: WB, P, IF
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 8
Application*: WB, P, IF
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat
Clone: CAP681
Application*: WB, IF, F, IH
Target: EIF4A1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 7H7
Application*: WB, P, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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