EIF4A1

EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Among its related pathways are Translation Translation regulation by Alpha-1 adrenergic receptors and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is EIF4A2.

Full Name

Eukaryotic Translation Initiation Factor 4A1

Alternative Names

Eukaryotic Translation Initiation Factor 4A1; ATP-Dependent RNA Helicase EIF4A-1; EIF-4A-I; EIF4A-I; EIF4A; DDX2A; Eukaryotic Translation Initiation Factor 4A, Isoform 1;

Research Area

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Biological Process

Cytoplasmic translational initiation Source: GO_Central

Cellular Location

Cytosol; Extracellular exosome; Cytoplasm; Eukaryotic translation initiation factor 4F complex; Membrane

Anti-EIF4A1 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-EIF4A1 Recombinant Antibody (CBT33) (V2LY-0625-LY3851)

Datasheet

SDS

Target: EIF4A1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBT33

Application*: WB, P, IF, IC

Rabbit Anti-EIF4A1 Recombinant Antibody (CBFYE-0696) (V2LY-0425-LY1711)

Datasheet

SDS

Target: EIF4A1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBFYE-0696

Application*: WB, IF, F

Rabbit Anti-EIF4A1 Recombinant Antibody (CBFYE-0693) (V2LY-0425-LY1710)

Datasheet

SDS

Target: EIF4A1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBFYE-0693

Application*: WB, P, IF, F

Mouse Anti-EIF4A1 Recombinant Antibody (EC138) (V2LY-0624-LY138)

Datasheet

SDS

Target: EIF4A1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EC138

Application*: WB, P, IF

Mouse Anti-EIF4A1 Recombinant Antibody (8) (CBMAB-EN1260-LY)

Datasheet

SDS

Target: EIF4A1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 8

Application*: WB, P, IF

Mouse Anti-EIF4A1 Recombinant Antibody (CAP681) (CBMAB-AP2035LY)

Datasheet

SDS

Target: EIF4A1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: CAP681

Application*: WB, IF, F, IH

Mouse Anti-EIF4A1 Recombinant Antibody (7H7) (CBMAB-Z0394-LY)

Datasheet

SDS

Target: EIF4A1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: 7H7

Application*: WB, P, IF

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)