EMSY

EMSY (EMSY, BRCA2 Interacting Transcriptional Repressor) is a Protein Coding gene. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer. Among its related pathways are Mesodermal Commitment Pathway.
Full Name
EMSY, BRCA2 Interacting Transcriptional Repressor
Research Area
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin (PubMed:14651845).

Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 (PubMed:14651845).

Mediates ligand-dependent transcriptional activation by nuclear hormone receptors (PubMed:19131338).
Biological Process
Chromatin organization Source: UniProtKB-KW
DNA repair Source: UniProtKB-KW
Regulation of transcription, DNA-templated Source: InterPro
Cellular Location
Nucleus. Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
PTM
O-glycosylated during cytokinesis at sites identical or close to phosphorylation sites, this interferes with the phosphorylation status.
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Anti-EMSY antibodies

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Mouse Anti-EMSY Recombinant Antibody (CBLC217-LY) (V2LY-0825-LY182)

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Target: EMSY
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBLC217-LY
Application*: WB, E, F
Datasheet SDS

Mouse Anti-EMSY Recombinant Antibody (CBFYE-0835) (V2LY-0825-LY181)

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Target: EMSY
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYE-0835
Application*: WB, E, F
Datasheet SDS

Mouse Anti-EMSY Recombinant Antibody (5D1) (CBMAB-A0926-LY)

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Target: EMSY
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 5D1
Application*: WB, E, IF
Datasheet SDS

Mouse Anti-EMSY Recombinant Antibody (CBFYE-0834) (CBMAB-E1289-FY)

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Target: EMSY
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0834
Application*: WB, IP, IF, E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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