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FBP2

This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]
Full Name
Fructose-Bisphosphatase 2
Research Area
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Biological Process
Fructose 1,6-bisphosphate metabolic process Source: GO_Central
Fructose 6-phosphate metabolic process Source: GO_Central
Fructose metabolic process Source: GO_Central
Gluconeogenesis Source: GO_Central
Sucrose biosynthetic process Source: GO_Central
Cellular Location
Cytoplasm; Nucleus; Cell junction; Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca2+ concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca2+ concentration.

Anti-FBP2 antibodies

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E10
Application*: WB, E
Target: FBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1244
Application*: WB
Target: FBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1245
Application*: WB, P
Target: FBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PAT1E11AT
Application*: E
Target: FBP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2887
Application*: E, WB
Target: FBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT1E11
Application*: E, WB
Target: FBP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CAP1032
Application*: Dot blot, ELISA, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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