FBP2

This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]
Full Name
Fructose-Bisphosphatase 2
Research Area
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Biological Process
Fructose 1,6-bisphosphate metabolic process Source: GO_Central
Fructose 6-phosphate metabolic process Source: GO_Central
Fructose metabolic process Source: GO_Central
Gluconeogenesis Source: GO_Central
Sucrose biosynthetic process Source: GO_Central
Cellular Location
Cytoplasm; Nucleus; Cell junction; Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca2+ concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca2+ concentration.
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Anti-FBP2 antibodies

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Mouse Anti-FBP2 Recombinant Antibody (CAP1032) (CBMAB-AP2216LY)

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CAP1032
Application*: Dot blot, ELISA, WB
Datasheet SDS

Mouse Anti-FBP2 Recombinant Antibody (CBXF-2887) (CBMAB-F3594-CQ)

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-2887
Application*: E, WB
Datasheet SDS

Mouse Anti-FBP2 Recombinant Antibody (AT1E11) (CBMAB-F2915-CQ)

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT1E11
Application*: E, WB
Datasheet SDS

Mouse Anti-FBP2 Recombinant Antibody (PAT1E11AT) (CBMAB-F1199-CQ)

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: PAT1E11AT
Application*: E
Datasheet SDS

Rabbit Anti-FBP2 Recombinant Antibody (CBXF-1245) (CBMAB-F0816-CQ)

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Target: FBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1245
Application*: WB, P
Datasheet SDS

Rabbit Anti-FBP2 Recombinant Antibody (CBXF-1244) (CBMAB-F0815-CQ)

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Target: FBP2
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1244
Application*: WB
Datasheet SDS

Mouse Anti-FBP2 Recombinant Antibody (1E10) (CBMAB-F0064-CQ)

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Target: FBP2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E10
Application*: WB, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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