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Rabbit Anti-FBP2 Recombinant Antibody (CBXF-1245) (CBMAB-F0816-CQ)

This product is a rabbit antibody that recognizes FBP2. The antibody CBXF-1245 can be used for immunoassay techniques such as: WB, IHC-P.
See all FBP2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
CBXF-1245
Antibody Isotype
IgG
Application
WB, IHC-P

Basic Information

Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Fructose-Bisphosphatase 2
Introduction
This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate.
Entrez Gene ID
Human8789
Mouse14120
Rat114508
UniProt ID
HumanO00757
MouseP70695
RatQ9Z1N1
Alternative Names
Fructose-Bisphosphatase 2; D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 2; Fructose-1,6-Bisphosphatase 2; Muscle FBPase; EC 3.1.3.11; FBPase 2;
Research Area
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Biological Process
Fructose 1,6-bisphosphate metabolic process Source: GO_Central
Fructose 6-phosphate metabolic process Source: GO_Central
Fructose metabolic process Source: GO_Central
Gluconeogenesis Source: GO_Central
Sucrose biosynthetic process Source: GO_Central
Cellular Location
Cytoplasm; Nucleus; Cell junction; Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca2+ concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca2+ concentration.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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