FCRL1

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Full Name
Fc Receptor Like 1
Research Area
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.
Biological Process
B cell activation Source: UniProtKB
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 17-307
Helical: 308-328
Cytoplasmic: 329-429
PTM
Phosphorylated on tyrosines upon activation.
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Anti-FCRL1 antibodies

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Target: FCRL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1734
Application*: WB
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0480
Application*: WB, F
Target: FCRL1
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: CBXF-3304
Application*: F
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-2593
Application*: WB, IP, IF, E
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-3305
Application*: WB, IP, IF, E
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4551
Application*: F
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2933
Application*: F
Target: FCRL1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0848
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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