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Mouse Anti-FCRL1 Recombinant Antibody (CBXF-0480) (V2LY-0925-LY1106)

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Basic Information

Host Animal
Mouse
Clone
CBXF-0480
Application
WB, FC
Immunogen
Recombinant human FCRL1/FcRH1 (Ala17-His304).
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1 µg/ml
FC0.25 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS & Trehalose
Preservative
None
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Fc Receptor Like 1
Entrez Gene ID
115350
UniProt ID
Q96LA6
Research Area
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.
Biological Process
B cell activation Source: UniProtKB
Cell surface receptor signaling pathway Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 17-307
Helical: 308-328
Cytoplasmic: 329-429
PTM
Phosphorylated on tyrosines upon activation.

Yousefi, Z., Sharifzadeh, S., Zare, F., & Eskandari, N. (2022). Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma. Molecular Biology Reports, 1-13.

DeLuca, J. M., Murphy, M. K., Wang, X., & Wilson, T. J. (2021). FCRL1 Regulates B Cell Receptor–Induced ERK Activation through GRB2. The Journal of Immunology, 207(11), 2688-2698.

DeLuca, J. M. (2021). The Multifaceted Role of FCRL1 in B Cell Signaling and Humoral Immunity (Doctoral dissertation, Miami University).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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