FKBP10

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. An alternatively spliced variant encoding different isoform has been found, but the biological validity of the variant is not determined. [provided by RefSeq]
Full Name
FK506 binding protein 10, 65 kDa
Function
PPIases accelerate the folding of proteins during protein synthesis.
Biological Process
Aorta morphogenesis Source: Ensembl
Collagen fibril organization Source: Ensembl
Extracellular matrix assembly Source: Ensembl
In utero embryonic development Source: Ensembl
Peptidyl-lysine hydroxylation Source: Ensembl
Peptidyl-proline modification Source: FlyBase
Wound healing Source: Ensembl
Cellular Location
Endoplasmic reticulum lumen
Involvement in disease
Osteogenesis imperfecta 11 (OI11):
A form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI11 is an autosomal recessive form.
Bruck syndrome 1 (BRKS1):
A disease characterized by generalized osteopenia, congenital joint contractures, fragile bones with onset of fractures in infancy or early childhood, short stature, severe limb deformity, progressive scoliosis, and pterygia.
PTM
Glycosylated and phosphorylated.
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Anti-FKBP10 antibodies

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Mouse Anti-FKBP10 Recombinant Antibody (3B5) (CBMAB-A2994-LY)

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Target: FKBP10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3B5
Application*: WB, E
Datasheet SDS

Mouse Anti-FKBP10 (AA 7-176) Recombinant Antibody (CBXF-3044) (CBMAB-F3746-CQ)

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Target: FKBP10
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3044
Application*: E, WB
Datasheet SDS

Mouse Anti-FKBP10 (AA 706-1052) Recombinant Antibody (CBXF-3043) (CBMAB-F3745-CQ)

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Target: FKBP10
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3043
Application*: E, WB
Datasheet SDS

Mouse Anti-FKBP10 Recombinant Antibody (CBXF-3042) (CBMAB-F3744-CQ)

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Target: FKBP10
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3042
Application*: E, WB
Datasheet SDS

Mouse Anti-FKBP10 Recombinant Antibody (CBXF-1970) (CBMAB-F1105-CQ)

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Target: FKBP10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human, Mouse
Clone: CBXF-1970
Application*: WB, IF, IH, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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