FUBP1

This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. [provided by RefSeq]

Full Name

far upstream element (FUSE) binding protein 1

Function

Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.

Biological Process

Positive regulation of gene expression Source: UniProtKB
Regulation of gene expression Source: GO_Central

Cellular Location

Nucleus

PTM

Ubiquitinated. This targets the protein for proteasome-mediated degradation.

Anti-FUBP1 antibodies

Mouse Anti-FUBP1 Recombinant Antibody (1E10) (CBMAB-A3220-LY)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1E10

Application*: WB, E

Rabbit Anti-FUBP1 Recombinant Antibody (CBXF-1099) (CBMAB-F0552-CQ)

Datasheet

SDS

Target: FUBP1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-1099

Application*: WB, P, F, IF

Rabbit Anti-FUBP1 Recombinant Antibody (CBXF-1098) (CBMAB-F0553-CQ)

Datasheet

SDS

Target: FUBP1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-1098

Application*: WB, IP, P, IF

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-0953) (CBMAB-F0989-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBXF-0953

Application*: WB, P, F, IF

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-1980) (CBMAB-F1609-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Dog, Mouse, Rat

Clone: CBXF-1980

Application*: WB, IF

Mouse Anti-FUBP1 Recombinant Antibody (3H4) (CBMAB-F2497-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3H4

Application*: E, IF, P, WB

Mouse Anti-FUBP1 Recombinant Antibody (14F5) (CBMAB-F2741-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 14F5

Application*: WB, F, E, IF

Mouse Anti-FUBP1 Recombinant Antibody (AT14F5) (CBMAB-F2913-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: AT14F5

Application*: E, IF, WB

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-0006) (CBMAB-F3219-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBXF-0006

Application*: E, WB

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-1807) (CBMAB-F3342-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-1807

Application*: WB, IP, IF, E

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-1808) (CBMAB-F3343-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-1808

Application*: WB, IP, IF, E

Mouse Anti-FUBP1 (AA 27-136) Recombinant Antibody (CBXF-3228) (CBMAB-F3923-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-3228

Application*: E, IF, WB

Mouse Anti-FUBP1 (AA 1-653) Recombinant Antibody (CBXF-3229) (CBMAB-F3924-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-3229

Application*: E, WB

Mouse Anti-FUBP1 Recombinant Antibody (CBXF-0954) (CBMAB-F4151-CQ)

Datasheet

SDS

Target: FUBP1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBXF-0954

Application*: E, IC, IF, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)