FUBP1
This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase. [provided by RefSeq]
Full Name
far upstream element (FUSE) binding protein 1
Function
Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.
Biological Process
Positive regulation of gene expression Source: UniProtKB
Regulation of gene expression Source: GO_Central
Regulation of gene expression Source: GO_Central
Cellular Location
Nucleus
PTM
Ubiquitinated. This targets the protein for proteasome-mediated degradation.
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Anti-FUBP1 antibodies
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CompareTarget: FUBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3228
Application*: IF, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-1808
Application*: WB, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-1807
Application*: WB, IF, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0006
Application*: WB, E, IH, IF
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Dog, Horse, Cattle
Clone: CBXF-1980
Application*: WB, IP, IF, E
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-0953
Application*: WB, IH, IF
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1098
Application*: WB, IP, IH, IF
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1099
Application*: WB, P, F, IF
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 7C3
Application*: E, WB, IH, IF, F, IP
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 1E10
Application*: WB, IP, IF, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0954
Application*: E, IC, IF, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-3229
Application*: WB, IP, IF, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3228
Application*: E, IF, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1808
Application*: WB, IP, IF, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1807
Application*: WB, IP, IF, E
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0006
Application*: E, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: AT14F5
Application*: E, IF, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 14F5
Application*: WB, F, E, IF
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3H4
Application*: E, IF, P, WB
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Mouse, Rat
Clone: CBXF-1980
Application*: WB, IF
Target: FUBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-0953
Application*: WB, P, F, IF
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1098
Application*: WB, IP, P, IF
Target: FUBP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1099
Application*: WB, P, F, IF
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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