LALBA

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.
Full Name
Lactalbumin Alpha
Function
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Defense response to bacteriumManual Assertion Based On ExperimentTAS:ProtInc
Lactose biosynthetic processManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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Anti-LALBA antibodies

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Mouse Anti-LALBA Recombinant Antibody (9E9) (CBMAB-A4543-YC)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Cattle
Clone: 9E9
Application*: WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (EC12) (V2LY-0624-LY12)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: EC12
Application*: WB, P, IF
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CB225A) (CBMAB-CA225LY)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB225A
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CB304) (CBMAB-CS304LY)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB304
Application*: WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CBYJL-1071) (CBMAB-L0511-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBYJL-1071
Application*: IH, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CBYJL-1070) (CBMAB-L0510-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-1070
Application*: E, EC
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (F20.16) (CBMAB-L0509-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: F20.16
Application*: WB, E, IC, IF
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CBYJL-1069) (CBMAB-L0508-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1069
Application*: WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (8L538) (CBMAB-L0507-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 8L538
Application*: IH, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (3B3) (CBMAB-L0506-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3B3
Application*: E
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (0.N.14) (CBMAB-L0505-YJ)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: 0.N.14
Application*: IC, IF, C, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (CBT5) (V2LY-0625-LY3877)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT5
Application*: WB, P, IF, IC
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (A856) (CBMAB-AP4187LY)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgM
Specificity: Bovine, Human
Clone: A856
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (A855) (CBMAB-AP4184LY)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A855
Application*: ELISA, WB
Datasheet SDS

Mouse Anti-LALBA Recombinant Antibody (A854) (CBMAB-AP484LY)

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Target: LALBA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A854
Application*: IF, IHC, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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