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Mouse Anti-LALBA Recombinant Antibody (9E9) (CBMAB-A4543-YC)

Provided herein is a Mouse monoclonal antibody against Human lactalbumin alpha. The antibody can be used for immunoassay techniques, such as WB.
See all LALBA antibodies

Summary

Host Animal
Mouse
Specificity
Human, Cattle
Clone
9E9
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human, Cattle
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Lactalbumin Alpha
Introduction
LALBA is alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enabl
Entrez Gene ID
Human3906
Cattle281894
UniProt ID
HumanP00709
CattleP00711
Alternative Names
LYZG
Function
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
Biological Process
Apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Cell-cell signalingManual Assertion Based On ExperimentTAS:ProtInc
Defense response to bacteriumManual Assertion Based On ExperimentTAS:ProtInc
Lactose biosynthetic processManual Assertion Based On ExperimentTAS:ProtInc
Signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted

Čítek, J., Samková, E., Brzáková, M., Hanuš, O., Večerek, L., Hoštičková, I., ... & Hálová, K. (2023). CSN1S1 and LALBA Polymorphisms and Other Factors Influencing Yield, Composition, Somatic Cell Score, and Technological Properties of Cow’s Milk. Animals, 13(13), 2079.

Sallam, A. M. (2023). Effect of genetic polymorphisms in LALBA and Prolactin genes on milk traits in Barki ewes. Small Ruminant Research, 226, 107041.

Fan, X. Y., Qiu, L. H., Zhang, Y. Y., Teng, X. H., & Miao, Y. W. (2021). Polymorphism, molecular characteristics of alpha-lactalbumin (LALBA) gene in river and swamp buffalo. Russian Journal of Genetics, 57, 836-846.

Ostrowska, M., Zwierzchowski, L., Brzozowska, P., Kawecka-Grochocka, E., Żelazowska, B., & Bagnicka, E. (2021). The effect of single-nucleotide polymorphism in the promoter region of bovine alpha-lactalbumin (LALBA) gene on LALBA expression in milk cells and milk traits of cows. Journal of Animal Science, 99(7), skab169.

Manzoor, S., Nadeem, A., & Javed, M. (2020). Polymorphism association and expression analysis of alpha-lactalbumin (LALBA) gene during lactation in Nili Ravi buffalo. Tropical Animal Health and Production, 52(1), 265-271.

Soyudal, B., Ardıçlı, S. E. N. A., Şamlı, H. A. L. E., Dinçel, D. E. N. İ. Z., & Balcı, F. (2019). Association of polymorphisms in the CSN2, CSN3, LGB and LALBA genes with milk production traits in Holstein cows raised in Turkey. Journal of the Hellenic Veterinary Medical Society, 69(4).

Crisà, A., Claps, S., Moioli, B., & Marchitelli, C. (2019). Identification of the complete coding cDNAs and expression analysis of B4GALT1, LALBA, ST3GAL5, ST6GAL1 in the colostrum and milk of the Garganica and Maltese goat breeds to reveal possible implications for oligosaccharide biosynthesis. BMC veterinary research, 15(1), 1-14.

Houaga, I. (2018). Polymorphisms in major milk protein genes (LALBA, MBLG, CSN1S1 and CSN3) and milk fat genes (DGAT1 and SCD1) and association with milk production and fatty acid traits in indigenous White Fulani and Borgou cattle breeds in Benin (Doctoral dissertation, JKUAT).

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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