MFRP

This gene encodes a member of the frizzled-related proteins. The encoded protein may play a role in eye development, as mutations in this gene have been associated with nanophthalmos, posterior microphthalmia, retinitis pigmentosa, foveoschisis, and optic disc drusen. The protein is encoded by a bicistronic mRNA, which also encodes C1q and tumor necrosis factor related protein 5

membrane frizzled-related protein

May play a role in eye development.

Embryo development ending in birth or egg hatching Source: UniProtKB
Eye photoreceptor cell development Source: Ensembl
Retina development in camera-type eye Source: Ensembl
Visual perception Source: Ensembl

Apical cell membrane

Nanophthalmos 2 (NNO2):
Rare autosomal recessive disorder of eye development characterized by extreme hyperopia and small functional eyes.
Microphthalmia, isolated, 5 (MCOP5):
A disorder characterized by posterior microphthalmia, retinitis pigmentosa, foveoschisis and optic disk drusen. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present.

Cytoplasmic: 1-69
Helical: 70-90
Extracellular: 91-579